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Recombinant Human Neurotrophin-3/NTF3 Protein

Uniprot : P20783
  • Cat.No.:PKSH032803

  • Expression host: E.coli

To Purchase PKSH032803

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  • 10µg
  • 50µg
Price: $178
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Description

Synonyms Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3
Species Human
Expression_host E.coli
Sequence Tyr139-Thr 257
Accession P20783
Application Functional ELISA
Mol_Mass 13.6 kDa
AP_Mol_Mass 14 kDa
Tag None
Bio_Activity Testing in progress

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin level < 0.01 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed man
Reconstitution Please refer to the printed manual for detailed information.

Background

Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems.

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