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RHOB Polyclonal Antibody

Cat:E-AB-12248
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse;Rat
  • Applications: WB
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Product Details
Verified Samples Verified Samples in WB:Mouse brain,Mouse fetal brain
Dilution

WB 1:1000-1:2000

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human RHOB
Abbre RHOB
Synonyms Aplysia RAS-related homolog 6;ARH6;ARHB;H6;MST081;MSTP081;oncogene RHO H6;ras homolog family member B;ras homolog gene family;member B;Rho cDNA clone 6;Rho related GTP binding protein RhoB Precursor;Rho-related GTP-binding protein RhoB;Rhob;RHOB;RHOH6
Swissprot
Calculated MW 22kDa
Cellular Localization Late endosome membrane. Cell membrane. Nucleus. Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus.
Concentration 0.4 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.