RHOB Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse;Rat
- Applications: WB
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Product Details
Verified Samples |
Verified Samples in WB:Mouse brain,Mouse fetal brain |
Dilution |
WB 1:1000-1:2000 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human RHOB |
Abbre | RHOB |
Synonyms | Aplysia RAS-related homolog 6;ARH6;ARHB;H6;MST081;MSTP081;oncogene RHO H6;ras homolog family member B;ras homolog gene family;member B;Rho cDNA clone 6;Rho related GTP binding protein RhoB Precursor;Rho-related GTP-binding protein RhoB;Rhob;RHOB;RHOH6 |
Swissprot | |
Calculated MW | 22kDa |
Cellular Localization | Late endosome membrane. Cell membrane. Nucleus. Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. |
Concentration | 0.4 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol