SH-PTP2 Polyclonal Antibody

Uniprot : Q06124
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14341

      Synonyms:BPTP3,CFC,JMML,METCDS,MGC14433,NS1,OTTHUMP00000166107,OTTHUMP00000166108,Protein tyrosine phosphatase 2,Protein tyrosine phosphatase 2C,Protein tyrosine phosphatase non receptor type 11,Protein-tyrosine phosphatase 1D,Protein-tyrosine phosphatase 2C,PTN11,PTP-1D,PTP-2C,PTP1D,PTP2C,PTPN11,SAP2,SH-PTP2,SH-PTP3,SH2 domain containing protein tyrosine phosphatase 2,SHP 2,SHP-2,Shp2,SHPTP2,SHPTP3,Syp,Tyrosine-protein phosphatase non-receptor type 11

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms BPTP3,CFC,JMML,METCDS,MGC14433,NS1,OTTHUMP00000166107,OTTHUMP00000166108,Protein tyrosine phosphatase 2,Protein tyrosine phosphatase 2C,Protein tyrosine phosphatase non receptor type 11,Protein-tyrosine phosphatase 1D,Protein-tyrosine phosphatase 2C,PTN11,PTP-1D,PTP-2C,PTP1D,PTP2C,PTPN11,SAP2,SH-PTP2,SH-PTP3,SH2 domain containing protein tyrosine phosphatase 2,SHP 2,SHP-2,Shp2,SHPTP2,SHPTP3,Syp,Tyrosine-protein phosphatase non-receptor type 11
      Swissprot Q06124
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human PTPN11
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:200-1:1000
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm.
      Tissue specificity Widely expressed, with highest levels in heart, brain, and skeletal muscle.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.

      Images

      Western Blot analysis of NIH/3T3 and hela cell using SH-PTP2 Polyclonal Antibody at dilution of 1:400

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