SOCS2 Polyclonal Antibody

Uniprot : O14508
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14356

      Synonyms:CIS 2,CIS-2,CIS2,Cish 2,Cish2,Cytokine inducible SH2 protein 2,Cytokine-inducible SH2 protein 2,SOCS 2,SOCS-2,Socs2,SOCS2,SSI 2,SSI-2,SSI2,STAT induced STAT inhibitor 2,STAT-induced STAT inhibitor 2,STATI 2,STATI2,Suppressor of cytokine signaling 2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CIS 2,CIS-2,CIS2,Cish 2,Cish2,Cytokine inducible SH2 protein 2,Cytokine-inducible SH2 protein 2,SOCS 2,SOCS-2,Socs2,SOCS2,SSI 2,SSI-2,SSI2,STAT induced STAT inhibitor 2,STAT-induced STAT inhibitor 2,STATI 2,STATI2,Suppressor of cytokine signaling 2
      Swissprot O14508
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human SOCS2
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:25-1:100
      Concentration 0.4 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytosol,Other locations:cytoplasm
      Tissue specificity High expression in heart, placenta, lung, kidney and prostate.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor.

      Images

      Immunohistochemistry of paraffin-embedded Human brain tissue using SOCS2 Polyclonal Antibody at dilution 1:40

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