TRIM23 Polyclonal Antibody (E-AB-18298)

For research use only.
Verified Samples |
Verified Samples in IHC: Human colorectal cancer, Human cervical cancer |
Dilution | IHC 1:35-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Fusion protein of human TRIM23 |
Abbre | TRIM23 |
Synonyms | ADP ribosylation factor domain protein 1, ADP-ribosylation factor domain-containing protein 1, ARF domain protein 1, ARFD1, E3 ubiquitin-protein ligase TRIM23, GTP binding protein ARD 1, GTP-binding protein ARD-1, N-acet, N-acetyltransferase ARD1 human homolog of |
Swissprot | |
Cellular Localization | Endomembrane system. Golgi apparatus membrane. Lysosome membrane. Membrane-associated with the Golgi complex and lysosomal structures. |
Concentration | 0.8 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Signal transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. |
Other Clones
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Other Formats
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Unconjugated
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