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For research use only.

Verified Samples Verified Samples in IHC: Human colorectal cancer, Human cervical cancer
Dilution IHC 1:35-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human TRIM23
Abbre TRIM23
Synonyms ADP ribosylation factor domain protein 1,  ADP-ribosylation factor domain-containing protein 1,  ARF domain protein 1,  ARFD1,  E3 ubiquitin-protein ligase TRIM23,  GTP binding protein ARD 1,  GTP-binding protein ARD-1,  N-acet,  N-acetyltransferase ARD1 human homolog of
Swissprot
Cellular Localization Endomembrane system. Golgi apparatus membrane. Lysosome membrane. Membrane-associated with the Golgi complex and lysosomal structures.
Concentration 0.8 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
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Unconjugated

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