CCL18/PARC Polyclonal Antibody(Capture/Detector) (AN004630P)
For research use only.
| Verified Samples | Verified Samples in ELISA: Recombinant Human CCL18/PARC protein, Human serum, Human plasma |
| Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | ELISA Capture/Detector |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human CCL18/PARC Protein expressed by E.coli |
| Abbre | CCL18/PARC |
| Synonyms | CKb, TSC, DCCK, DC-CK, Eotaxin, AMAC-1, CCL26, CKb7, DC-CK1, Eotaxin-3, IMAC, MIP-4, MIP-4a, SCYA26, TSC-1, AMAC1, MIP4, PARC, SCYA18, CCL18, AMAC-1, CKb7, DCCK1, DC-CK1, MIP-4, Alternative macrophage activation associated CC chemokine 1, Alternative macrophage activation-associated CC chemokine 1, CC chemokine PARC, C-C Motif Chemokine 18, CCL18(4-69), Dendritic cell chemokine 1, Macrophage inflammatory protein 4, Pulmonary and activation regulated chemokine, Pulmonary and activation-regulated chemokine, Small inducible cytokine A18, Small-inducible cytokine A18 |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Immunology |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | CCL18, also known as alternative macrophage activation-associated CC chemokine (AMAC)-1, macrophage inflammatory protein (MIP)-4, and dendritic cell chemokine (DC-CK1), is a novel CC chemokine that is highly homologous to MIP-1 alpha (61% amino acid (aa) sequence identity). CCL18 cDNA encodes an 89 aa residue precursor protein with a 20 aa putative signal peptide that is cleaved to generate a 69 aa residue mature protein which lacks potential glycosylation sites. In vitro, CCL18 mRNA expression is induced in alternatively activated macrophages by Th2 cytokines such as IL-4, IL-10, and IL-13, and inhibited by IFN‑ gamma. CCL18 mRNA is also expressed by GM-CSF/IL-4-induced monocyte-derived dendritic cells. In vivo, CCL18 is highly expressed in lung and placenta but is not expressed in epidermal Langerhans cells. Recombinant CCL18 has been shown to chemoattract naive T cells but not monocytes or neutrophils. |
Other Clones
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Unconjugated
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