CD27/TNFRSF7 Polyclonal Antibody(Capture/Detector) (AN004010P)
For research use only.
| Verified Samples | Verified Samples in ELISA: Recombinant Mouse CD27/TNFRSF7 protein, Mouse serum, Mouse plasma, Human serum, Human plasma, Rat serum, Rat plasma |
| Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA Capture/Detector |
| Clonality | Polyclonal |
| Immunogen | Recombinant Mouse CD27/TNFRSF7 Protein expressed by Mammalian |
| Abbre | CD27/TNFRSF7 |
| Synonyms | Tnfrsf, Tnfrsf7, Cd27, T14, S152, TNFRSF7, CD27 antigen, CD27L receptor, S152, T-cell activation antigen CD27, Tp55, Tumor necrosis factor receptor superfamily member 7 |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis. |
Other Clones
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Other Formats
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Unconjugated
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