CRMP1 Polyclonal Antibody (E-AB-12333)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse brain |
| Dilution | WB 1:500-1:1000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human CRMP1 |
| Abbre | CRMP1 |
| Synonyms | CRMP 1, CRMP-1, Collapsin response mediator protein 1, Crmp1, DPYL1, DPYSL1, DRP 1, DRP-1, DRP1, Dihydropyrimidinase like 1, Dihydropyrimidinase related protein 1, Dihydropyrimidinase-related protein 1, ULIP-3, Ulip3, Unc-33-like phosphoprotein 3 |
| Swissprot | |
| Calculated MW | 62 kDa |
| Cellular Localization | Cytoplasm. Cytoplasm>cytoskeleton>centrosome. Cytoplasm>cytoskeleton>spindle. Associated with centrosomes and the mitotic spindle during metaphase. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Collapsin response mediator protein 1, encoded by the CRMP1 gene, is a human protein of the CRMP family.This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system.The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development.Alternative splicing results in multiple transcript variants.CRMP1 mediates reelin signaling in cortical neuronal migration.Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory.CRMP1 gene overlaps with another gene called EVC.CRMP1 has been shown to interact with DPYSL2. |
Other Clones
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Other Formats
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Unconjugated
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