Erythropoietin/EPO Monoclonal Antibody(Capture) (AN001960P)
For research use only.
Verified Samples | Verified Samples in ELISA: Recombinant Mouse Erythropoietin/EPO protein, Mouse serum, Mouse plasma |
Dilution | ELISA Capture 2-8 μg/mL |
Isotype | IgG2a |
Host | Rat |
Reactivity | Mouse |
Applications | ELISA Capture |
Clonality | Monoclonal |
Immunogen | Recombinant Mouse Erythropoietin/EPO protein expressed by E.coli |
Abbre | Erythropoietin/EPO |
Synonyms | MGC, ECYT, MVCD, Hematopoietin, Hemopoietin, ECYT5, EP, epoetin, Erythropoietin, MGC138142, MVCD2, Epo |
Swissprot | |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Purification Method | Protein A/G Purification |
Research Areas | Cancer, Cardiovascular, Metabolism, Developmental biology, Signal transduction, Stem cells |
Clone No. | 8C3 |
Conjugation | Unconjugated |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
background | This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. |
Other Clones
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Unconjugated
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