GANAB Polyclonal Antibody (E-AB-53418)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human colorectal cancer, Human prostate cancer |
| Dilution | IHC 1:50-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human GANAB |
| Abbre | GANAB |
| Synonyms | Alpha glucosidase II alpha subunit, Alpha-glucosidase 2, G2AN, GANAB, Glu II, GluII, Glucosidase II alpha, Glucosidase II subunit alpha, Glucosidase alpha neutral AB, KIAA0088, Neutral alpha glucosidase AB, Neutral alpha glucosidase AB precursor, Neutral alpha- |
| Swissprot | |
| Cellular Localization | Endoplasmic reticulum. Golgi apparatus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Concentration | 0.72 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. |
Other Clones
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Other Formats
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Unconjugated
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