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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human thyroid cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human IAPP
Abbre IAPP
Synonyms Amylin,  DAP,  Diabetes associated peptide,  Diabetes-associated peptide,  IAP,  IAPP,  Insulinoma amyloid peptide,  Islet amyloid polypeptide,  Islet amyloid polypeptide (diabetes associated peptide,  amylin)
Swissprot
Cellular Localization Secreted.
Concentration 0.8 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
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Unconjugated

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