IRF4 Polyclonal Antibody (E-AB-13342)

For research use only.
Verified Samples |
Verified Samples in WB: Jurkat |
Dilution | WB 1:200-1:1000 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | WB |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human IRF4 |
Abbre | IRF4 |
Synonyms | IRF 4, IRF-4, IRF4, Interferon regulatory factor 4, Irf4, LSIRF, Lymphocyte specific IRF, Lymphocyte specific interferon regulatory factor, Lymphocyte-specific interferon regulatory factor, MUM 1, MUM1, Multiple myeloma oncogene 1, NF EM5, NF-EM5, NFEM5, PU.1 interactio |
Swissprot | |
Calculated MW | 52 kDa |
Cellular Localization | Nucleus. |
Concentration | 0.2 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling, Tags and Cell Markers |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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