LDL Monoclonal Antibody(Detector) (AN001910P)
For research use only.
| Verified Samples | Verified Samples in ELISA: Recombinant Human LDL protein, Human serum, Human plasma |
| Dilution | ELISA Detector 0.1-0.4 μg/mL |
| Isotype | Mouse IgG2a |
| Host | Mouse |
| Reactivity | Human |
| Applications | ELISA Detector |
| Clonality | Monoclonal |
| Immunogen | Human LDL Native Protein |
| Abbre | LDL |
| Synonyms | LDL, Low-Density Lipoprotein, |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Protein A/G Purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Signal transduction |
| Clone No. | 4E1 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol,an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis. Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits. It has been shown that the family of LDL receptors may serve as viral receptors. |
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Unconjugated
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