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Neuropilin-1 Polyclonal Antibody(Capture/Detector) (AN000740P)

All Size Price Qty
100μg $ 350.00
25μg $ 130.00
1mg Inquire /
Add to cart

For research use only.

Verified Samples Verified Samples in ELISA: Recombinant Human Neuropilin-1 protein, Human serum, Human plasma
Dilution ELISA Capture 2-8 μg/mL,  ELISA Detector 0.1-0.4 μg/mL
Isotype Rabbit IgG
Host Rabbit
Reactivity Human
Applications ELISA Capture/Detector
Clonality Polyclonal
Immunogen Recombinant Human Neuropilin-1 protein expressed by Mammalian
Abbre Neuropilin-1
Synonyms Neuropilin-1,  Vascular endothelial cell growth factor 165 receptor,  CD304,  NRP1,  NRP,  VEGF165R
Swissprot
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
Purification Method Antigen Affinity Purification
Research Areas Cardiovascular,  Neuroscience,  Immunology
Conjugation Unconjugated
Storage Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
background Neuropilin-1 (Npn-1, previously neuropilin; also CD304) is a 130 - 140 kDa type I transmembrane (TM) glycoprotein that regulates axon guidance and angiogenesis. Two homologues, Neuropilin-1 and Neuropilin-2, are identified. Neuropilin-1 binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. NRP1 expression is regulated in EC by tumor necrosis factor-alpha, the transcription factors dHAND and Ets-1, and vascular injury. NRP1 upregulation is positively correlated with the progression of various tumors.
Other Clones

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Unconjugated

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