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For research use only.

Verified Samples Verified Samples in WB: RAW264.7
Verified Samples in IHC: Human colon cancer, Human thyroid cancer
Dilution WB 1:200-1:1000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human NFKBID
Abbre NFKBID
Synonyms I-kappa-B-delta,  IKBD,  IKBNS,  IkB-delta,  IkappaBNS,  IkappaBdelta,  NF-kappa-B inhibitor delta,  NFKBID,  Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor delta,  T-cell activation NFKB-like protein,  TA-NFKBH
Swissprot
Calculated MW 33 kDa
Cellular Localization Nucleus.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Epigenetics and Nuclear Signaling,  Immunology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.
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Unconjugated

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