Recombinant Carbonic Anhydrase XII/Car12 Monoclonal Antibody (AN300457P)
For research use only.
| Verified Samples | Verified Samples in IHC: Mouse kidney, Mouse intestine |
| Dilution | IHC-P 1:100-1:500 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Mouse |
| Applications | IHC-P |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse Carbonic Anhydrase XII/CA12 Protein |
| Abbre | CA12 |
| Synonyms | Car, Carbonic anhydrase, Carbonate dehydratase XII, Carbonic anhydrase 12, Carbonic anhydrase XII, CAXII, CA-XII, Car12, Ca12 |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Clone No. | 7B7 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA12, also known as Car12 and carbonic anhydrase XII, is a type I membrane enzyme of an N-terminal extracellular catalytic domain, a membrane-spanning α-helix, and a small intracellular C-terminal domain. It is highly expressed in colon, kidney, prostate, intestine and activated lymphocytes and moderately expressed in pancreas, ovary, and testis. Overexpression of the CA12 is observed in certain human cancers and is used as a tumor marker. rmCA12 corresponds to the extracellular domain and has both carbonic anhydrase activity and esterase activity. |
Other Clones
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Unconjugated
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