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100μL $ 380.00
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For research use only.

Verified Samples Verified Samples in IHC: Human kidney, Human liver
Dilution IHC-P 1:100-1:500,  
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC-P
Clonality Rabbit Monoclonal
Immunogen Recombinant Human GCSH Protein
Abbre GCSH
Synonyms GCSH,  GCE,  NKH,  Glycine cleavage system H protein,  Glycine cleavage system H protein mitochondrial,  Glycine cleavage system protein H,  Glycine cleavage system protein H (aminomethyl carrier),  Lipoic acid containing protein,  mitochondrial,  Mitochondrial glycine cleavage system H protein
Swissprot
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Protein A
Research Areas Tags & Cell Markers,  Signal Transduction,  Metabolism
Clone No. 14B8
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.
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Unconjugated

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