Recombinant SIGNR1/CD209b Monoclonal Antibody (AN300523P)
For research use only.
| Verified Samples |
Verified Samples in IF: Mouse splenocytes Verified Samples in FCM: BABL/c splenocytes |
| Dilution | ICC/IF 1:20-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Mouse |
| Applications | ICC/IF |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse SIGNR1/CD209b protein |
| Abbre | CD209B |
| Synonyms | OtB, DC-SIGN-related protein, DC-SIGNR, CD209, CD209 antigen-like protein B, DC-SIGNR1, DC-SIGN-related protein 1, OtB7, Cd209b |
| Swissprot | |
| Tissue Specificity | Expressed in skin, spleen and lung, probably in a subset of dendritic cells. Detected in spleen extrafollicular paracortical areas including the red pulp and marginal zones, and at lower levels, in the follicular area. Detected in skin suprabasal areas adjacent to the epidermis and in epidermal cell layer. |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Clone No. | 8A1 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway. |
Other Clones
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Other Formats
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Unconjugated
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