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For research use only.

Verified Samples Verified Samples in IF: U2OS
Dilution IF 1:50-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Rat
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human RPS6KB1 (NP_003152.1).
Abbre RPS6KB1
Synonyms P70 S6K,  PS6K,  RPS6KB1,  S6K,  S6K-beta-1,  S6K1,  STK14A,  p70 S6KA,  p70(S6K)-alpha,  p70-S6K,  p70-alpha,  p70S6KA
Swissprot
Cellular Localization Cytoplasm, Nucleus, Cytoplasm and Cell junction>synapse>synaptosome, Mitochondrion outer membrane.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Epigenetics and Nuclear Signaling,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Other Clones

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Unconjugated

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