RUVBL1 Polyclonal Antibody (E-AB-66239)
For research use only.
| Verified Samples |
Verified Samples in IF: U2OS |
| Dilution | IF 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human RUVBL1 (NP_003698.1). |
| Abbre | RUVBL1 |
| Synonyms | ECP-54, ECP54, INO80H, NMP 238, NMP238, PONTIN, Pontin52, RUVBL1, RVB1, TIH1, TIP49, TIP49A |
| Swissprot | |
| Cellular Localization | Nucleus matrix, Nucleus, nucleoplasm, Cytoplasm, Membrane, Cytoplasm, cytoskeleton, centrosome, Mainly localized in the nucleus, associated with nuclear matrix or in the nuclear cytosol, although it is also present in the cytoplasm and associated with the cell membranes, In prophase and prometaphase it is located at the centrosome and the branching microtubule spindles, After mitotic nuclear membrane disintigration it accumulates at the centrosome and sites of tubulin polymerization, As cells pass through metaphase and into telophase it is located close to the centrosome at the early phase of tubulin polymerization, In anaphase it accumulates at the zone of tubule interdigitation, In telophase it is found at polar tubule overlap, and it reappears at the site of chromosomal decondensation in the daughter cells. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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