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For research use only.

Verified Samples Verified Samples in WB: Jurkat
Verified Samples in IHC: Human colon cancer, Human liver cancer
Dilution WB 1:200-1:1000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human TRAF3IP2
Abbre TRAF3IP2
Synonyms ACT1,  Act 1,  Activator of cAMP responsive element modulator (CREM) in testis,  Adapter protein CIKS,  C6ORF4,  C6ORF5,  C6ORF6,  CIKS,  Chromosome 6 Open Reading Frame 4,  Chromosome 6 Open Reading Frame 5,  Chromosome 6 Open Reading Frame 6,  Connection to IKK and SAPK / JN
Swissprot
Calculated MW 65 kDa
Cellular Localization Other locations: intracellular.
Concentration 0.3 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
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Unconjugated

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