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For research use only.

Verified Samples Verified Samples in WB: A375, Hela, Jurkat
Verified Samples in IHC: Human skin
Dilution WB 1:500-1:2000,  IHC 1:50-200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human TYR
Abbre TYR
Synonyms ATN,  CMM8,  LB24 AB,  LB24-AB,  Monophenol monooxygenase,  OCA1,  OCA1A,  OCAIA,  Oculocutaneous albinism IA,  SHEP3,  SK29 AB,  SK29-AB,  TYR,  TYRO,  Tumor rejection antigen AB,  Tyrosinase,  tyrosinase (oculocutaneous albinism IA)
Swissprot
Calculated MW 60 kDa
Cellular Localization Melanosome membrane.
Concentration 0.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Signal Transduction,  Tags and Cell Markers
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
Other Clones

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Unconjugated

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