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(KO Validated) EIF4E Polyclonal Antibody

Cat:E-AB-60650
Manual MSDS
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Price: $ 580

Price: $ 360

Price: $ 220

Size:
200μL 120μL 60μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse;Rat
  • Applications: IHC;IF
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For research use only. Order now, ship in 3 days

Product Details
Verified Samples Verified Samples in IHC:Human lung cancer,Human stomach
Verified Samples in IF:U2OS
Dilution

IHC 1:50-1:100, IF 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen A synthetic peptide of human EIF4E (NP_001959.1).
Abbre EIF4E
Synonyms AUTS19;CBP;EIF4E1;EIF4EL1;EIF4F;eIF-4E;EIF4E
Swissprot
Cellular Localization Cytosol,Extracellular region or secreted,extracellular exosome,Other locations:chromatoid body,cytoplasm,cytoplasmic ribonucleoprotein granule,cytoplasmic stress granule,eukaryotic translation initiation factor 4F complex,mRNA cap binding complex,P-body,perinuclear region of cytoplasm,RISC complex
Concentration 1mg/mL
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method Affinity purification
Research Areas Cancer; Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Ice bag
background The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.