(KO Validated) EIF4E Polyclonal Antibody
- +1
Price: $ 580
Price: $ 360
Price: $ 220
Size:
200μL
120μL
60μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse;Rat
- Applications: IHC;IF
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For research use only. Order now, ship in 3 days
Product Details
Verified Samples |
Verified Samples in IHC:Human lung cancer,Human stomach Verified Samples in IF:U2OS |
Dilution |
IHC 1:50-1:100, IF 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | A synthetic peptide of human EIF4E (NP_001959.1). |
Abbre | EIF4E |
Synonyms | AUTS19;CBP;EIF4E1;EIF4EL1;EIF4F;eIF-4E;EIF4E |
Swissprot | |
Cellular Localization | Cytosol,Extracellular region or secreted,extracellular exosome,Other locations:chromatoid body,cytoplasm,cytoplasmic ribonucleoprotein granule,cytoplasmic stress granule,eukaryotic translation initiation factor 4F complex,mRNA cap binding complex,P-body,perinuclear region of cytoplasm,RISC complex |
Concentration | 1mg/mL |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method | Affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Ice bag |
background | The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol