ADRM1 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human; Mouse; Rat
- Applications: IHC
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Product Details
Verified Samples |
Verified Samples in IHC:Human tonsil,Human thyroid cancer |
Dilution |
IHC 1:40-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Fusion protein of human ADRM1 |
Abbre | ADRM1 |
Synonyms | 110 kDa cell membrane glycoprotein;adhesion regulating molecule 1;Adhesion-regulating molecule 1;ADRM 1;Adrm1;ADRM1;ARM 1;ARM-1;ARM1;Gp110;hRpn13;M(r) 110;000 surface antigen;Proteasomal ubiquitin receptor ADRM1;proteasome regulatory particle non ATPase 13;Proteasome regulatory particle non-ATPase 13;Regulatory particle non ATPase 13;Rpn13;Rpn13 homolog |
Swissprot | |
Cellular Localization | Cytoplasm. Nucleus. |
Concentration | 0.54 mg/mL |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Ice bag |
background | The 26S proteasome is a key component of the ubiquitin-proteasome system,a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme,UCH37,and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol