Purified Anti-Human CD273 Antibody[24F.10C12], Functional Grade (E-AB-F11750)
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For research use only.
| Alternate Names | PDL, PD-L, PD-1 ligand, PDCD1 ligand, Programmed death ligand, Programmed cell death 1 ligand, PDCD1L, bA574F, PDCD1LG, B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2, PDCD1LG2, B7-DC, Butyrophilin B7-DC, Programmed cell death 1 ligand 2, PD-1 ligand 2, PDCD1 ligand 2, Programmed death ligand 2, PDL2, PD-L2, B7 dendritic cell molecule, Butyrophilin B7 DC, Butyrophilin B7DC, CD 273, CD273 antigen, MGC142238, MGC142240, PD 1 ligand 2, PD L2, PD1 ligand 2, PD1L2, PDCD 1 ligand 2, PDL 2 |
| Clone | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Human CD273 gene |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells);FA Reported in the literature |
| Background | T cells require a signal induced by the engagement of the T cell receptor and a “co‑stimulatory” signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. Members of the B7 superfamily of counter-receptors were identified by their ability to interact with co‑stimulatory molecules found on the surface of T cells. Members of the B7 superfamily include B7-1 (CD80), B7-2 (CD86), B7-H1 (PD-L1), B7-H2 (B7RP-1), B7-H3, and PD-L2 (B7-DC). None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Human CD273 protein |
| Abbre | CD273 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG2a, κ |
| Isotype Control | Purified Mouse IgG2a, κ Isotype Control[C1.18.4], Functional Grade |
| Applications |
FCM;FA
|
| Research Areas | Immunology |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Application References | Brown JA, et al. J Immunol. 2003 Feb;170:1257. Rodig N, et al. Eur J Immunol. 2003 Nov;33:3117. |
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