Purified Anti-Mouse CD1d Antibody[19G11], Functional Grade (E-AB-F10320)
![Purified Anti-Mouse CD1d Antibody[19G11], Functional Grade - 1](http://file.elabscience.com/assets/images/loading.png)
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For research use only.
| Alternate Names | Antigen-presenting glycoprotein CD1d, Antigen-presenting glycoprotein CD1d1, CD1d.1, Cd1.1, Cd1d1, CD1, Ly-38, CD1.1, CD1.2, AI747460, Cd1a, Cd1d, Ly-38 |
| Clone | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells);Neut Reported in the literature |
| Background | CD1d is a type I transmembrane protein and member of the MHC family, with a molecular weight ranging from 43-49 kD, depending on the glycosylation degree. CD1d is expressed by antigen presenting cells such as dendritic cells, monocytes, macrophages and B cells; also expressed by thymocytes and intestinal epithelial cells. CD1d present glycolipids to iNKT cells that recognize them by their Vα14i TCR. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Mouse CD1d protein |
| Abbre | CD1d |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rat IgG1,κ |
| Isotype Control | Purified Rat IgG1, κ Isotype Control[HRPN], Functional Grade |
| Applications |
FCM;Neut
|
| Research Areas | Immunology;Innate Immunity |
| Cellular Localization |
Cell membrane, Endosomes and lysosomes
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Application References | Torsten Olszak, et al. Nature. 2014 May 22;509(7501):497-502. |
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