Elab Fluor® 488 Anti-Human CD107a/LAMP-1 Antibody[H4A3] (E-AB-F1149L)
![Elab Fluor<sup>®</sup> 488 Anti-Human CD107a/LAMP-1 Antibody[H4A3] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: Elab Fluor®488
APC Elab Fluor®488 Elab Fluor®700 FITC PE PE/Elab Fluor®594 PerCP/Cyanine 5.5 Unconjugated Show More
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD107a/LAMP-1 |
| Synonyms | LAMP-1LGP-120, Lysosome-Associated Membrane Protein 1, LAMP-1 |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Biology, Immunology, Neurodegeneration, Neuroscience, Protein Trafficking and Clearance |
| Clone No. | H4A3 |
| Conjugation | Elab Fluor®488 |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity. |
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