AIF1 Polyclonal Antibody
- +1
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse;Rat
- Applications: WB;IHC
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Product Details
Verified Samples |
Verified Samples in WB:Mouse kidney Verified Samples in IHC:Human breast cancer,Human cervical cancer |
Dilution |
WB 1:200-1:1000, IHC 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human AIF1 |
Abbre | AIF1 |
Synonyms | AIF 1;AIF-1;Aif1;AIF1 protein;AIF1;Allograft inflammatory factor 1;Allograft inflammatory factor 1 splice variant G;allograft inflammatory factor-1 splice variant Hara-1;balloon angioplasty responsive transcription;BART 1;G1;G1 putative splice variant of allograft inflamatory factor 1;IBA 1;IBA1;interferon gamma responsive transcript;Interferon responsive transcript 1;interferon responsive transcript factor 1;Ionized calcium binding adapter molecule 1;Ionized calcium-binding adapter molecule 1;ionized calcium-binding adapter molecule;IRT 1;IRT1;Microglia response factor;MRF1;Protein g1 |
Swissprot | |
Calculated MW | 17kDa |
Cellular Localization | Cytoplasm>cytoskeleton. Cell projection>ruffle membrane. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. |
Concentration | 0.6 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cell Biology; Metabolism; Immunology; Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
Citations
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The appearance of phagocytic microglia in the postnatal brain of Niemann Pick type C mice is developmentally regulated and underscores shortfalls in fine odor discrimination
IF:6.513
Journal:JOURNAL OF CELLULAR PHYSIOLOGY
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol