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AKAP12 Polyclonal Antibody

Cat:E-AB-12884
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human brain,Human lung cancer
Dilution

IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human AKAP12
Abbre AKAP12
Synonyms A kinase (PRKA) anchor protein (gravin) 12;A kinase Anchor Protein 12;A kinase anchor protein 250kDa;A-kinase anchor protein 12;A-kinase anchor protein 250 kDa;AKA12;AKAP 12;AKAP 250;AKAP-12;Akap12;AKAP250;DKFZp686M0430;DKFZp686O0331;FLJ20945;FLJ97621;Gercelin;Gravin;Kinase scaffold protein gravin;Myasthenia gravis autoantigen;Myasthenia gravis autoantigen gravin;OTTHUMP00000017426;OTTHUMP00000017427;Src-Suppressed C Kinase Substrate;Srcs5;SSeCKS;Tsga12
Swissprot
Cellular Localization Cytoplasm>cell cortex. Cytoplasm>cytoskeleton. May be part of the cortical cytoskeleton.
Concentration 0.4 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Neuroscience; Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.