AKAP12 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human
- Applications: IHC
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Product Details
Verified Samples |
Verified Samples in IHC:Human brain,Human lung cancer |
Dilution |
IHC 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human AKAP12 |
Abbre | AKAP12 |
Synonyms | A kinase (PRKA) anchor protein (gravin) 12;A kinase Anchor Protein 12;A kinase anchor protein 250kDa;A-kinase anchor protein 12;A-kinase anchor protein 250 kDa;AKA12;AKAP 12;AKAP 250;AKAP-12;Akap12;AKAP250;DKFZp686M0430;DKFZp686O0331;FLJ20945;FLJ97621;Gercelin;Gravin;Kinase scaffold protein gravin;Myasthenia gravis autoantigen;Myasthenia gravis autoantigen gravin;OTTHUMP00000017426;OTTHUMP00000017427;Src-Suppressed C Kinase Substrate;Srcs5;SSeCKS;Tsga12 |
Swissprot | |
Cellular Localization | Cytoplasm>cell cortex. Cytoplasm>cytoskeleton. May be part of the cortical cytoskeleton. |
Concentration | 0.4 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Neuroscience; Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol