ASL Polyclonal Antibody

Uniprot : P04424
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14601

      Synonyms:Argininosuccinase,Argininosuccinate lyase,Arginosuccinase,ARLY,ASAL,ASL,EC 4.3.2.1

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Argininosuccinase,Argininosuccinate lyase,Arginosuccinase,ARLY,ASAL,ASL,EC 4.3.2.1
      Swissprot P04424
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human ASL
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytosol,Extracellular region or secreted,extracellular exosome,Other locations:cytoplasm
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. 

      Images

      Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ASL Polyclonal Antibody at dilution 1:35

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ASL Polyclonal Antibody at dilution 1:35

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