ATXN1 Polyclonal Antibody

Uniprot : P54253
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14779

      Synonyms:alternative ataxin1,Ataxin-1,ATX1,ATX1,Atxn1,D6S504E,OTTHUMP00000016065,SCA1,Spinocerebellar ataxia type 1 protein

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms alternative ataxin1,Ataxin-1,ATX1,ATX1,Atxn1,D6S504E,OTTHUMP00000016065,SCA1,Spinocerebellar ataxia type 1 protein
      Swissprot P54253
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human ATXN1
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Nucleus. Colocalizes with USP7 in the nucleus.
      Tissue specificity Widely expressed throughout the body.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. 

      Images

      Western Blot analysis of 293T cell and Human fetal brain tissue using ATXN1 Polyclonal Antibody at dilution of 1:800

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using ATXN1 Polyclonal Antibody at dilution of 1:40

      Immunohistochemistry of paraffin-embedded Human liver cancer using ATXN1 Polyclonal Antibody at dilution of 1:40

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