For research use only.
Background | CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID). |
Alternate Names | CD132, Cytokine receptor common subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, Il2rg, Interleukin-2 receptor subunit gamma, gammaC, p64 |
Swissprot | |
Clone No | |
Host | Rat |
Reactivity | Mouse |
Isotype | Rat IgG2b, κ |
Isotype Control | |
Application |
FCM
|
Form | Liquid |
Conjugation | Biotin |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Expiration date | 12 months |
Shipping | Ice bag |
Other Clones
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Biotin
Unconjugated
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