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Biotin Anti-Mouse CD132 Antibody[3E12]

Uniprot : P34902
  • Cat.No.:E-AB-F1015B

  • Applications: FCM
  • Isotype: Rat IgG2b, κ
  • Host: Rat

To Purchase E-AB-F1015B

Size:
  • 25μg
  • 100μg
Price: $40
Qty:

Antigen Details

Alternate Names Cytokine receptor common subunit gamma,Il2rg,Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64,CD132
Swissprot P34902
References
1. Itano M, et al. 1996. Tohoku J. Exp. Med. 178:389.
2. Zola H, et al. eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley & Sons Inc, Publication .
3. Nakarai T, et al. 1994. J. Exp. Med. 180:241.
4. Kawahara A, et al. 1995. Proc. Natl. Acad. Sci. USA. 92:8724.
5. Habib T, et al. 2002. Biochemistry. 41:8725.
6. Matthews DJ, et al. 1995. Blood 85:38.

Product Details

Form Liquid
Clone No. 3E12
Host Rat
Isotype Rat IgG2b, κ
Isotype Control Biotin Rat IgG2b, κ Isotype Control[LTF-2] [Product E-AB-F09843B]
Reactivity Mouse
Application FCM
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8°C. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation Biotin

How to select the appropriate detection channel through the spectrogram?

Background

CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Product Name Sizes Price
AF/LE Purified Anti-Mouse CD132 Antibody[3E12] 50μg, 500μg, 1mg Check More
Purified Anti-Mouse CD132 Antibody[3E12] 25μg, 100μg Check More

Citations

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