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CASP10 Polyclonal Antibody

Cat:E-AB-13820
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human liver cancer,Human lung cancer
Dilution

IHC 1:25-1:100

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human CASP10
Abbre CASP10
Synonyms ALPS2;Apoptotic protease Mch-4;CASP 10;CASP-10;CASP10;CASPA;Caspase 10 apoptosis related cysteine peptidase;Caspase-10 subunit p12;FADD like ICE2;Fas associated death domain protein;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE 2;FLICE2;ICE like apoptotic protease 4;ICE-like apoptotic protease 4;Interleukin 1B converting enzyme 2;MCH 4
Swissprot
Cellular Localization Cytosol,ripoptosome,Plasma Membrane,CD95 death-inducing signaling complex
Concentration 0.2 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Cell Biology; Metabolism
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.