CASP10 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human
- Applications: IHC
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Product Details
Verified Samples |
Verified Samples in IHC:Human liver cancer,Human lung cancer |
Dilution |
IHC 1:25-1:100 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human CASP10 |
Abbre | CASP10 |
Synonyms | ALPS2;Apoptotic protease Mch-4;CASP 10;CASP-10;CASP10;CASPA;Caspase 10 apoptosis related cysteine peptidase;Caspase-10 subunit p12;FADD like ICE2;Fas associated death domain protein;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE 2;FLICE2;ICE like apoptotic protease 4;ICE-like apoptotic protease 4;Interleukin 1B converting enzyme 2;MCH 4 |
Swissprot | |
Cellular Localization | Cytosol,ripoptosome,Plasma Membrane,CD95 death-inducing signaling complex |
Concentration | 0.2 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cell Biology; Metabolism |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol