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CAST Polyclonal Antibody

Cat:E-AB-11022
Manual MSDS
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Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human
  • Applications: WB;IHC
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Product Details
Verified Samples Verified Samples in WB:LoVo
Verified Samples in IHC:Human gastric cancer,Human colon cancer
Dilution

WB 1:500-1:2000, IHC 1:100-1:300

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human CAST
Abbre CAST
Synonyms BS 17;Calpain inhibitor;Calpastatin;Cast;Heart type calpastatin;ICAL;MGC9402;Sperm BS 17 component;Sperm BS-17 component
Swissprot
Calculated MW 77kDa
Cellular Localization Cytosol,Endoplasmic reticulum,endoplasmic reticulum,Other locations:membrane
Concentration 0.8 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Cell Biology; Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.