CBY1 Polyclonal Antibody

Uniprot : Q9Y3M2
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14716

      Synonyms:ARPP-binding protein,C22orf2,CBY,Cby1,CBY1,Cytosolic leucine rich protein,Cytosolic leucine-rich protein,Golgi and endoplasmic reticulum-associated 1,HRIHFB2025,PIGEA 14,PIGEA-14,PKD2 interactor,PKD2 interactor,Golgi and endoplasmic reticulum-associated 1,Protein Chibby,Protein chibby homolog 1

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms ARPP-binding protein,C22orf2,CBY,Cby1,CBY1,Cytosolic leucine rich protein,Cytosolic leucine-rich protein,Golgi and endoplasmic reticulum-associated 1,HRIHFB2025,PIGEA 14,PIGEA-14,PKD2 interactor,PKD2 interactor,Golgi and endoplasmic reticulum-associated 1,Protein Chibby,Protein chibby homolog 1
      Swissprot Q9Y3M2
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human CBY1
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.6 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus speckle. Golgi apparatus, trans-Golgi network. Nuclear, in a punctate manner. Also found in the trans-Golgi.
      Tissue specificity Widely expressed. Expressed at higher levels in heart, skeletal muscle, kidney and placenta. Also found in brain, lung, liver and testis. Significantly down-regulated in thyroid and metastatic uterine tumors.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CBY1 Polyclonal Antibody at dilution 1:60

      Immunohistochemistry of paraffin-embedded Human brain tissue using CBY1 Polyclonal Antibody at dilution 1:60

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