CLDND2 Polyclonal Antibody

Uniprot : Q8NHS1

Catalog number:E-AB-17706

Synonyms:Claudin domain containing 2,Claudin domain containing protein 2,PMP22CD

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Price: $69

Host: Rabbit

Reactivity: H,M

Applications: IHC,ELISA

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Synonyms	Claudin domain containing 2,Claudin domain containing protein 2,PMP22CD
Swissprot	Q8NHS1
Source	Rabbit
Reactivity	Human,Mouse
Immunogen	Synthetic peptide of human CLDND2
Application	IHC,ELISA
Recommended dilution	IHC 1:30-150, ELISA 1:2000-10000
Concentration	1.4 mg/mL
Clonality	Polyclonal

Cellular localization	Cell Membrane
Isotype	IgG
Purification	Affinity purification
Conjugation	Unconjugated
Storage instructions	Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer	PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background	CLDND2 (claudin domain containing 2) is a 167 amino acid multi-pass membrane protein that belongs to the PMP-22/EMP/MP20 family and is encoded by a gene that maps to human chromosome 19q13.33. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19.