DKC1 Polyclonal Antibody (E-AB-64375)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human lung cancer Verified Samples in IF: NIH/3T3, U-2OS |
| Dilution | IHC 1:50-1:100, IF 1:50-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC, IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human DKC1 (NP_001354.1). |
| Abbre | DKC1 |
| Synonyms | CBF5, DKC, DKC1, DKCX, NAP57, NOLA4, XAP101 |
| Swissprot | |
| Cellular Localization | Cytoplasm and Nucleus>nucleolus. Nucleus>Cajal body. Also localized to Cajal bodies. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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