FAT1 Polyclonal Antibody (E-AB-13237)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human FAT1 |
| Abbre | FAT1 |
| Synonyms | Cadherin ME5, Cadherin family member 7, Cadherin family member 7 precursor, Cadherin related tumor suppressor, Cadherin related tumor suppressor homolog, Cadherin related tumor suppressor homolog precursor, Cadherin related tumor suppressor homolog precursor (F |
| Swissprot | |
| Cellular Localization | Cell membrane. Nucleus. Cytoplasm>perinuclear region. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development.The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats.In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain.This gene is expressed at high levels in a number of fetal epithelia.Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication.Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. |
Other Clones
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Other Formats
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Unconjugated
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