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HSP40 Polyclonal Antibody

Cat:E-AB-14642
Manual MSDS
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Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse
  • Applications: WB;IHC
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For research use only. Order now, ship in 3 days

Product Details
Verified Samples Verified Samples in WB:293T
Verified Samples in IHC:Human lung cancer,Human gastric cancer
Dilution

WB 1:500-1:2000, IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human DNAJB1
Abbre DNAJB1
Synonyms DnaJ (Hsp40) homolog subfmaily B member 1;DNAJ 1;DNAJ B1;DnaJ heat shock protein family (Hsp40) member B1;DnaJ homolog subfamily B member 1;DnaJ protein homolog 1;DNAJ1;DNAJB 1;Dnajb1;DNAJB1 protein;DNJB1;HDJ 1;HDJ-1;HDJ1;Heat shock 40 kDa protein 1;Heat shock 40kD protein 1;Heat shock protein 40;Hsp 40;HSP40;HSPF 1;HSPF1;Human DnaJ protein 1;Radial spoke 16 homolog B;RSPH16B;Sis1
Swissprot
Calculated MW 38kDa
Cellular Localization Cytoplasm. Nucleus. Nucleus>nucleolus. Translocates rapidly from the cytoplasm to the nucleus, and especially to the nucleoli, upon heat shock.
Concentration 0.3 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background Heat shock protein 40 (HSP 40) family proteins bind to HSP 70 through their J-domain and regulate the function of HSP 70 by stimulating HSP 70 ATPase activity. HSP 40, also known as DnaJ, functions together with DnaK (HSP 70) and GrpE as a molecular chaperone, involving them in assembly and disassembly of protein complexes, protein folding, renaturation of denatured proteins, prevention of protein aggregation and protein export. HSP 40 stimulates the association between HSC 70 and HIP and translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock. There are five known HSP 40 family proteins.