KLC1 Polyclonal Antibody

Uniprot : Q07866
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14710

      Synonyms:Kinesin 2 60/70kDa,Kinesin light chain 1,Kinesin2,KLC 1,KLC,Klc1,KLC1,KNS 2,KNS 2A,KNS2,KNS2A,Medulloblastoma antigen MU MB 2.50,MGC15245

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Kinesin 2 60/70kDa,Kinesin light chain 1,Kinesin2,KLC 1,KLC,Klc1,KLC1,KNS 2,KNS 2A,KNS2,KNS2A,Medulloblastoma antigen MU MB 2.50,MGC15245
      Swissprot Q07866
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human KLC1
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:200-1:1000, IHC 1:25-1:100
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm>cytoskeleton.
      Tissue specificity Found in a variety of tissues. Mostly abundant in brain and spine.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.

      Images

      Western Blot analysis of Lovo cell using KLC1 Polyclonal Antibody at dilution of 1:550

      Immunohistochemistry of paraffin-embedded Human colon cancer using KLC1 Polyclonal Antibody at dilution of 1:40

      Immunohistochemistry of paraffin-embedded Human lung cancer using KLC1 Polyclonal Antibody at dilution of 1:40

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      MSDS for ELISA

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