MAP2K6 Polyclonal Antibody

Uniprot : P70236
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-40167

      Synonyms:MEK6,MKK6,MAPKK6,PRKMK6,SAPKK3,SAPKK-3

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $60

      Host: Rabbit

      Reactivity: M,R

      Applications: IHC

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms MEK6,MKK6,MAPKK6,PRKMK6,SAPKK3,SAPKK-3
      Swissprot P70236
      Source Rabbit
      Reactivity Mouse,Rat
      Immunogen Recombinant Mouse Dual specificity mitogen-activated protein kinase kinase 6 protein
      Application IHC(Detection kit: E-IR-R217)
      Recommended dilution IHC 1:50-1:100
      Concentration 2mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoskeleton,Cytosol,Nucleus,nucleoplasm,nucleus,Other locations:cytoplasm
      Tissue specificity Isoform 2 is only expressed in skeletal muscle. Isoform 1 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
      Background This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

      Images

      polyclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Mouse brain using MAP2K6 Polyclonal Antibody at dilution of 1:50

      polyclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Rat brain using MAP2K6 Polyclonal Antibody at dilution of 1:50

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