MMP25 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human
- Applications: IHC
Add to cart
For research use only. Order now, ship in 3 days
Product Details
Verified Samples |
Verified Samples in IHC:Human brain |
Dilution |
IHC 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human MMP25 |
Abbre | MMP25 |
Synonyms | Leukolysin;matrix metallopeptidase 25;matrix metallopeptidase like 1;matrix metalloproteinase 20;Matrix Metalloproteinase 25;Matrix metalloproteinase 25 precursor;Matrix metalloproteinase-25;Membrane type 6 Matrix Metalloproteinase;Membrane type Matrix Metalloproteinase 6;Membrane-type matrix metalloproteinase 6;Membrane-type-6 matrix metalloproteinase;MMP 25;MMP-25;MMP20;MMP20A;MMP25;MMP25;MMPL1;MT-MMP 6;MT6-MMP;MT6MMP;MTMMP6 |
Swissprot | |
Cellular Localization | Cell membrane. Secreted, extracellular space, extracellular matrix. |
Concentration | 0.5 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cell Biology; Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol