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Mouse IL-6(Interleukin 6) ELISA Kit

Citations(483)Uniprot : P08505

  • Cat.No.:E-EL-M0044

  • Reactivity: Mouse
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Manual MSDS

To Purchase E-EL-M0044

Size:
  • 96T
  • 48T
  • 24T
  • 96T*5
  • 96T*10
Price: $495
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Product Details

Properties

Assay type Sandwich-ELISA
Format 96T/48T
Assay time 3.5h
Detection range 31.25-2000 pg/mL
Sensitivity 18.75 pg/mL
Sample type &Sample volume serum, plasma and other biological fluids; 100μL
Specificity This kit recognizes Mouse IL-6 in samples. No significant cross-reactivity or interference between Mouse IL-6 and analogues was observed.
Reproducibility Both intra-CV and inter-CV are < 10%.
Application This ELISA kit applies to the in vitro quantitative determination of Mouse IL-6 concentrations in serum, plasma and other biological fluids.

Test Principle

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse IL-6. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Mouse IL-6 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse IL-6, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Mouse IL-6. You can calculate the concentration of Mouse IL-6 in the samples by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for 1 month. If the kit is not supposed to be used within 1 month, store the components separately according to the following conditions once the kit is received.
ItemSpecificationsStorage
Micro ELISA Plate(Dismountable) 96T: 8 wells ×12 strips
48T: 8 wells ×6 strips 		-20℃, 6 months
Reference Standard 96T: 2 vials
48T: 1 vial
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL
48T: 1 vial, 60 μL
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL
48T: 1 vial, 60 μL 		-20℃(Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL
HRP Conjugate Diluent 1 vial, 14 mL
Concentrated Wash Buffer (25×) 1 vial, 30 mL
Substrate Reagent 1 vial, 10 mL 2-8℃(Protect from light)
Stop Solution 1 vial, 10 mL 2-8°C
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Technical Data

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Mouse IL-6 were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Mouse IL-6 were tested on 3 different plates, 20 replicates in each plate.

  Intra-assay Precision Inter-assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (pg/mL) 99.40 174.50 952.80 105.30 162.70 1040.70
Standard deviation 6.40 7.70 50.50 6.50 8.10 38.50
CV (%) 6.44 4.41 5.30 6.17 4.98 3.70

Recovery

The recovery of Mouse IL-6 spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 86-100 93
EDTA plasma (n=8) 88-101 94
Cell culture media (n=8) 89-104 95

Linearity

Samples were spiked with high concentrations of Mouse IL-6 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

Target Information

Database LinksSwissProt:   P08505
SynonymsIL6, BSF2, HGF, HSF, IFNB2, CDF
Research AreaCancer, Metabolism, Immunology, Neuroscience

Assay Procedures

elisa assay procedure 1

1. Add 100μL standard or sample to the wells. Incubate for 90 min at 37°C
elisa assay procedure 2

2. Discard the liquid, immediately add 100μL Biotinylated Detection Ab working solution to each well. Incubate for 60 min at 37°C
elisa assay procedure 3

3. Aspirate and wash the plate for 3 times
elisa assay procedure 4

4. Add 100μL HRP conjugate working solution. Incubate for 30 min at 37°C. Aspirate and wash the plate for 5 times
elisa assay procedure 5

5. Add 90μL Substrate Reagent. Incubate for 15 min at 37°C
elisa assay procedure 6

6. Add 50μL Stop Solution
elisa assay procedure 7

7. Read the plate at 450nm immediately. Calculation of the results

Citations

  1. BRAIN BEHAVIOR AND IMMUNITY (2022) IF: 19.227
    Intestinal dysbiosis mediates cognitive impairment via the intestine and brain NLRP3 inflammasome activation in chronic sleep deprivation

    DOI: 10.1016/j.bbi.2022.11.013

    PMID: 36427810

    		 Sample: serum
  2. ACS Nano (2023) IF: 18.027
    Sensitizing Tumors to Immune Checkpoint Blockage via STING Agonists Delivered by Tumor-Penetrating Neutrophil Cytopharmaceuticals

    DOI: 10.1021/acsnano.2c11764

    PMID: 36595464

    		 Sample: serum
  3. ACS Central Science (2023) IF: 18.728
    Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury

    DOI: 10.1021/acscentsci.2c01424

    PMID: 36968547

    		 Sample: bronchoalveolar lavage fluid (BALF),lung
  4. KIDNEY INTERNATIONAL (2022) IF: 18.998
    Cellular communication network 2 (connective tissue growth factor) aggravates acute DNA damage and subsequent DNA damage response-senescence-fibrosis following kidney ischemia reperfusion injury

    DOI: 10.1016/j.kint.2022.06.030

    PMID: 35921911

    		 Sample: RPTEC
  5. CHEMICAL ENGINEERING JOURNAL (2022) IF: 16.744
    Tumor microenvironment activated nanoreactors for chemiluminescence imaging-guided simultaneous elimination of breast tumors and tumor-resident intracellular pathogens

    DOI: 10.1016/j.cej.2022.139939
    Sample: infectious tissues
  6. CHEMICAL ENGINEERING JOURNAL (2022) IF: 16.744
    Lyophilization-inactivated cancer cells composited Janus scaffold for tumor postoperative immuno-chemotherapy

    DOI: 10.1016/j.cej.2022.140619
    Sample: Bone marrow-derived dendritic cell (BMDC)
  7. ADVANCED FUNCTIONAL MATERIALS (2020) IF: 16.836
    Quantitative Photoacoustic Diagnosis and Precise Treatment of Inflammation In Vivo Using Activatable Theranostic Nanoprobe

    DOI: 10.1002/adfm.202001771
    Sample: Serum
  8. Small (2023) IF: 15.153
    Oral Metal-Free Melanin Nanozymes for Natural and Durable Targeted Treatment of Inflammatory Bowel Disease (IBD)

    DOI: 10.1002/smll.202207350
    Sample: colon tissue
  9. Small (2022) IF: 15.153
    Kidney-Targeted Nanoparticles Loaded with the Natural Antioxidant Rosmarinic Acid for Acute Kidney Injury Treatment

    DOI: 10.1002/smll.202204388

    PMID: 36253133

    		 Sample: kidney
  10. Arthritis & Rheumatology (2022) IF: 15.483
    NLRP3 attenuates intraocular inflammation by inhibiting AIM2 mediated pyroptosis through the P-SIK1/SREBF1 pathway

    DOI: 10.1002/art.42420
    Sample: BMDMs
  11. npj Regenerative Medicine (2022) IF: 14.404
    Enforced mesenchymal stem cell tissue colonization counteracts immunopathology

    DOI: 10.1038/s41536-022-00258-z

    PMID: 36261464

    		 Sample: plasma,AdMSCs
  12. MOLECULAR CELL (2017) IF: 14.714
    Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy

    DOI: 10.1016/j.molcel.2017.03.008
    Sample: Serum
  13. Science Advances (2022) IF: 14.957
    Glucocorticoid-induced loss of beneficial gut bacterial extracellular vesicles is associated with the pathogenesis of osteonecrosis

    DOI: 10.1126/sciadv.abg8335
    Sample: serum
  14. CHEMICAL ENGINEERING JOURNAL (2022) IF: 13.273
    2D MoSe2@PVP nanosheets with multi-enzyme activity alleviate the acute pancreatitis via scavenging the reactive oxygen and nitrogen species

    DOI: 10.1016/j.cej.2022.136792
    Sample: serum
  15. Bone Research (2019) IF: 13.567
    Extracellular vesicles from human urine-derived stem cells prevent osteoporosis by transferring CTHRC1 and OPG

    DOI: 10.1038/s41413-019-0056-9
    Sample: serum
  16. JOURNAL OF PINEAL RESEARCH (2023) IF: 12.081
    Melatonin inhibits atherosclerosis progression via Galectin-3 downregulation to enhance autophagy and inhibit inflammation

    DOI: 10.1111/jpi.12855
    Sample: serum
  17. Bone Research (2018) IF: 12.354
    Omentin-1 prevents inflammation-induced osteoporosis by downregulating the pro-inflammatory cytokines

    DOI: 10.1038/s41413-018-0012-0
    Sample: Serum
  18. Journal for ImmunoTherapy of Cancer (2022) IF: 12.469
    Nanoparticle delivery of miR-21-3p sensitizes melanoma to anti-PD-1 immunotherapy by promoting ferroptosis

    DOI: 10.1136/jitc-2021-004381

    PMID: 35738798

    		 Sample: B16F10 cell-xenograft
  19. Advanced Healthcare Materials (2022) IF: 11.092
    Switchable ROS Scavenger/Generator for MRI-Guided Anti-Inflammation and Anti-Tumor Therapy with Enhanced Therapeutic Efficacy and Reduced Side Effects

    DOI: 10.1002/adhm.202202043
    Sample: serum
  20. Theranostics (2022) IF: 11.556
    Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy

    DOI: 10.7150/thno.68667

    PMID: 35547755

    		 Sample: blood
  21. Nano Research (2022) IF: 10.269
    Peptide nanotube loaded with a STING agonist, c-di-GMP, enhance cancer immunotherapy against melanoma

    DOI: 10.1007/s12274-022-5102-z
  22. JOURNAL OF NANOBIOTECHNOLOGY (2022) IF: 10.435
    Intracellular marriage of bicarbonate and Mn ions as “immune ion reactors” to regulate redox homeostasis and enhanced antitumor immune responses

    DOI: 10.1186/s12951-022-01404-x
    Sample: serum
  23. JOURNAL OF NANOBIOTECHNOLOGY (2021) IF: 10.435
    Gold nanoparticles reduce inflammation in cerebral microvessels of mice with sepsis

    DOI: 10.1186/s12951-021-00796-6

    PMID: 33608025

    		 Sample: Tissue（brain）
  24. Acta Biomaterialia (2023) IF: 10.633
    Targeted therapy for peri-prosthetic osteolysis using macrophage membrane-encapsulated human urine-derived stem cell extracellular vesicles

    DOI: 10.1016/j.actbio.2023.02.003
    Sample: RAW264.7 cell,osteoclasto
  25. Bioengineering & Translational Medicine (2022) IF: 10.711
    Baicalein self-microemulsion based on drug–phospholipid complex for the alleviation of cytokine storm

    DOI: 10.1002/btm2.10357
    Sample: plasma
  26. CARBOHYDRATE POLYMERS (2022) IF: 10.723
    Aloe polymeric acemannan inhibits the cytokine storm in mouse pneumonia models by modulating macrophage metabolism

    DOI: 10.1016/j.carbpol.2022.120032

    PMID: 36184177

    		 Sample: bronchoalveolar fluid,RAW264.7 cell
  27. ACS Applied Materials & Interfaces (2022) IF: 9.2289
    Bioactive Injectable Hydrogel Dressings for Bacteria-Infected Diabetic Wound Healing: A “Pull–Push” Approach

    DOI: 10.1021/acsami.2c04300
    Sample: regenerated wound samples
  28. BRITISH JOURNAL OF PHARMACOLOGY (2022) IF: 9.4730
    Repurposing nitazoxanide as a novel anti-atherosclerotic drug based on mitochondrial uncoupling mechanisms

    DOI: 10.1111/bph.15949

    PMID: 36082580

    		 Sample: serum
  29. ENVIRONMENTAL POLLUTION (2022) IF: 9.988
    Developmental exposure to chlorpyrifos causes neuroinflammation via necroptosis in mouse hippocampus and human microglial cell line

    DOI: 10.1016/j.envpol.2022.120217

    PMID: 36155221

    		 Sample: hippocampi
  30. Cell Reports (2023) IF: 9.9949
    RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.

    DOI: 10.1016/j.celrep.2023.112097
    Sample: serum,RAW264.7 cell
  31. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 8.025
    Structural characterization of a soluble polysaccharide SSPS1 from soy whey and its immunoregulatory activity in macrophages

    DOI: 10.1016/j.ijbiomac.2022.07.043

    PMID: 35835298

    		 Sample: Raw 264.7 macrophages
  32. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 8.025
    A glycoprotein from mountain cultivated ginseng: Insights into their chemical characteristics and intracellular antioxidant activity

    DOI: 10.1016/j.ijbiomac.2022.07.023

    PMID: 35817242

    		 Sample: RAW264.7 cell
  33. Journal of Neuroinflammation (2021) IF: 8.3219
    Sirtuin 3 protects against anesthesia/surgery-induced cognitive decline in aged mice by suppressing hippocampal neuroinflammation

    DOI: 10.1186/s12974-021-02089-z

    PMID: 33541361

    		 Sample: Tissue homogenate(Hippocampal homogenate)
  34. Journal of Neuroinflammation (2022) IF: 8.3219
    Far infrared light irradiation enhances Aβ clearance via increased exocytotic microglial ATP and ameliorates cognitive deficit in Alzheimer’s disease-like mice

    DOI: 10.1186/s12974-022-02521-y
    Sample: brain
  35. Cell Death & Disease (2022) IF: 8.4689
    Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32

    DOI: 10.1038/s41419-022-04962-y

    PMID: 35739102

    		 Sample: RAW264.7 cell
  36. Cell Death & Disease (2020) IF: 8.4689
    MicroRNA-377-3p released by mesenchymal stem cell exosomes ameliorates lipopolysaccharide-induced acute lung injury by targeting RPTOR to induce autophagy

    DOI: 10.1038/s41419-020-02857-4
    Sample: BALF
  37. Cell Death & Disease (2021) IF: 8.4689
    Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesity

    DOI: 10.1038/s41419-021-04308-0

    PMID: 34716308

    		 Sample: Raw264.7 cell
  38. Theranostics (2020) IF: 8.5790
    Engineering blood exosomes for tumor-targeting efficient gene/chemo combination therapy

    DOI: 10.7150/thno.45028

    PMID: 32685027

    		 Sample: Serum
  39. Frontiers in Immunology (2022) IF: 8.786
    Bifidobacterium breve intervention combined with environmental enrichment alleviates cognitive impairment by regulating the gut microbiota and microbial metabolites in Alzheimer's disease mice.

    DOI: 10.3389/fimmu.2022.1013664
    Sample: Hippocampal tissue
  40. Cellular and Molecular Gastroenterology and Hepatology (2022) IF: 8.7970
    Klebsiella pneumoniae induces inflammatory bowel disease through caspase-11-mediated IL-18 in the gut epithelial cells

    DOI: 10.1016/j.jcmgh.2022.11.005
    Sample: colon tissue
  41. CHEMOSPHERE (2022) IF: 8.943
    Oral administration of Bacillus cereus GW-01 alleviates the accumulation and detrimental effects of β-cypermethrin in mice

    DOI: 10.1016/j.chemosphere.2022.137333
    Sample: serum
  42. International Journal of Nanomedicine (2022) IF: 7.033
    Biocompatible Assessment of Erythrocyte Membrane-Camouflaged Polymeric PLGA Nanoparticles in Pregnant Mice: Both on Maternal and Fetal/Juvenile Mice

    DOI: 10.2147/IJN.S384906
    Sample: serum
  43. CNS Neuroscience & Therapeutics (2023) IF: 7.035
    Dl-3-n-butylphthalide promotes synaptic plasticity by activating the Akt/ERK signaling pathway and reduces the blood–brain barrier leakage by inhibiting the HIF-1α/MMP signaling pathway in vascular dementia model mice

    DOI: 10.1111/cns.14112
    Sample: brain tissue
  44. FOOD HYDROCOLLOIDS (2020) IF: 7.053
    Generation of structurally diverse pectin oligosaccharides having prebiotic attributes

    DOI: 10.1016/j.foodhyd.2020.105988
    Sample: RAW 264.7 cell
  45. CHEMOSPHERE (2020) IF: 7.086
    Interleukin 17A deficiency alleviates fluoride-induced testicular injury by inhibiting the immune response and apoptosis

    DOI: 10.1016/j.chemosphere.2020.128178
    Sample: interstitial fluid
  46. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022) IF: 7.088
    Discovery of fusidic acid derivatives as novel STING inhibitors for treatment of sepsis

    DOI: 10.1016/j.ejmech.2022.114814

    PMID: 36228412

    		 Sample: RAW264.7 cells
  47. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022) IF: 7.088
    Design and synthesis of hederagenin derivatives modulating STING/NF-κB signaling for the relief of acute liver injury in septic mice

    DOI: 10.1016/j.ejmech.2022.114911
  48. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2023) IF: 7.129
    Acute liver injury induced by carbon tetrachloride reversal by Gandankang aqueous extracts through nuclear factor erythroid 2-related factor 2 signaling pathway

    DOI: 10.1016/j.ecoenv.2023.114527
    Sample: liver,serum
  49. Acta Biomaterialia (2020) IF: 7.242
    Near-infrared/pH dual-responsive nanocomplexes for targeted imaging and chemo/gene/photothermal tri-therapies of non-small cell lung cancer

    DOI: 10.1016/j.actbio.2020.03.004

    PMID: 32151700

    		 Sample: Whole Blood
  50. Oxidative Medicine and Cellular Longevity (2023) IF: 7.31
    RRP Regulates Autophagy through the AMPK Pathway to Alleviate the Effect of Cell Senescence on Atherosclerosis

    DOI: 10.1155/2023/9645789
    Sample: serum
  51. Oxidative Medicine and Cellular Longevity (2022) IF: 7.31
    Inositol Alleviates Pulmonary Fibrosis by Promoting Autophagy via Inhibiting the HIF-1α-SLUG Axis in Acute Respiratory Distress Syndrome

    DOI: 10.1155/2022/1030238
    Sample: serum,Human pulmonary alveolar epithelial cells (H
  52. Oxidative Medicine and Cellular Longevity (2022) IF: 7.31
    Downregulation of SIRT3 Aggravates Lung Ischemia Reperfusion Injury by Increasing Mitochondrial Fission and Oxidative Stress through HIF-1α-Dependent Mechanisms

    DOI: 10.1155/2022/9041914
    Sample: left lung tissue,bronchoalveolar lavage fluid (BAL
  53. FREE RADICAL BIOLOGY AND MEDICINE (2022) IF: 7.376
    Inhibition of neuronal nitric oxide synthase protects against hippocampal neuronal injuries by increasing neuropeptide Y expression in temporal lobe epilepsy mice

    DOI: 10.1016/j.freeradbiomed.2022.06.221

    PMID: 35714846

    		 Sample: hippocampal tissue
  54. FREE RADICAL BIOLOGY AND MEDICINE (2021) IF: 7.376
    ADAM10 suppresses demyelination and reduces seizure susceptibility in cuprizone-induced demyelination model

    DOI: 10.1016/j.freeradbiomed.2021.05.001

    PMID: 33965566

    		 Sample: Tissue homogenate
  55. BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 7.419
    Xiaojianzhong decoction attenuates gastric mucosal injury by activating the p62/Keap1/Nrf2 signaling pathway to inhibit ferroptosis

    DOI: 10.1016/j.biopha.2022.113631

    PMID: 36122518

    		 Sample: gastric mucosal tissue,
  56. BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 7.419
    Study on a novel enzymatic colon-targeted particle of total saponins of Pulsatilla by mechanical grinding technology in a solvent free system

    DOI: 10.1016/j.biopha.2022.113645

    PMID: 36115109

    		 Sample: colon tissue
  57. BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 7.419
    Psoralen suppresses the phosphorylation of amyloid precursor protein (APP) to inhibit myelosuppression

    DOI: 10.1016/j.biopha.2022.113381

    PMID: 36076476

    		 Sample: MSCs
  58. BIOMEDICINE & PHARMACOTHERAPY (2023) IF: 7.419
    Phillygenin inhibited M1 macrophage polarization and reduced hepatic stellate cell activation by inhibiting macrophage exosomal miR-125b-5p

    DOI: 10.1016/j.biopha.2023.114264
    Sample: RAW264.7 cell
  59. BIOMEDICINE & PHARMACOTHERAPY (2023) IF: 7.419
    Innovative challenge for the inhibition of hepatocellular carcinoma progression by combined targeting of HSP90 and STAT3/HIF-1α signaling

    DOI: 10.1016/j.biopha.2022.114196
    Sample: liver tissue
  60. BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 7.419
    1-Deoxynojirimycin attenuates septic cardiomyopathy by regulating oxidative stress, apoptosis, and inflammation via the JAK2/STAT6 signaling pathway

    DOI: 10.1016/j.biopha.2022.113648

    PMID: 36108388

    		 Sample: serum
  61. FOOD RESEARCH INTERNATIONAL (2022) IF: 7.425
    Physicochemical characteristics and biological activities of soluble dietary fibers isolated from the leaves of different quinoa cultivars

    DOI: 10.1016/j.foodres.2022.112166
  62. FOOD CHEMISTRY (2021) IF: 7.514
    Premna microphylla Turcz leaf pectin exhibited antioxidant and anti-inflammatory activities in LPS-stimulated RAW 264.7 macrophages

    DOI: 10.1016/j.foodchem.2021.129164

    PMID: 33550022

    		 Sample: Cell culture medium
  63. Frontiers in Immunology (2022) IF: 7.561
    PHLDA1 Suppresses TLR4-Triggered Proinflammatory Cytokine Production by Interaction With Tollip

    DOI: 10.3389/fimmu.2022.731500
    Sample: RAW264.7 cell,Bone marrow-derived macrophages
  64. Frontiers in Immunology (2021) IF: 7.561
    Interplay Between Sialic Acids, Siglec-E, and Neu1 Regulates MyD88- and TRIF-Dependent Pathways for TLR4-Activation During Leishmania donovani Infection

    DOI: 10.3389/fimmu.2021.626110

    PMID: 33763070

    		 Sample: Cell culture supernatant
  65. Frontiers in Immunology (2021) IF: 7.561
    IL-27 Mediates Pro-Inflammatory Effects via the ERK Signaling Pathway During Preterm Labor

    DOI: 10.3389/fimmu.2021.709229

    PMID: 34691022

    		 Sample: serum
  66. Biomaterials Science (2022) IF: 7.59
    Single-component lipid nanoparticles for engineering SOCS1 gene-silenced dendritic cells to boost tumor immunotherapy

    DOI: 10.1039/D2BM01549H
    Sample: serum
  67. Antioxidants (2023) IF: 7.675
    Structural Optimization of Cannabidiol as Multifunctional Cosmetic Raw Materials

    DOI: 10.3390/antiox12020314
    Sample: RAW264.7 cell
  68. Antioxidants (2022) IF: 7.675
    Genipin Attenuates Diabetic Cognitive Impairment by Reducing Lipid Accumulation and Promoting Mitochondrial Fusion via FABP4/Mfn1 Signaling in Microglia

    DOI: 10.3390/antiox12010074
    Sample: hippocampal tissues
  69. Antioxidants (2022) IF: 7.675
    Comprehensive Effect of Carbon Tetrachloride and Reversal of Gandankang Formula in Mice Liver: Involved in Oxidative Stress, Excessive Inflammation, and Intestinal Microflora

    DOI: 10.3390/antiox11112234
    Sample: liver,serum
  70. AMERICAN JOURNAL OF CHINESE MEDICINE (2022) IF: 6.005
    Sinapic Acid Alleviates Acute Pancreatitis in Association with Attenuation of Inflammation, Pyroptosis, and the AMPK/NF-κ B Signaling Pathway

    DOI: 10.1142/S0192415X2250094X
    Sample: serum
  71. FREE RADICAL BIOLOGY AND MEDICINE (2018) IF: 6.02
    Procyanidin B2 ameliorates free fatty acids-induced hepatic steatosis through regulating TFEB-mediated lysosomal pathway and redox state

    DOI: 10.1016/j.freeradbiomed.2018.08.024
    Sample: serum
  72. ANALYTICAL CHEMISTRY (2018) IF: 6.042
    A Redox-Responsive Self-Assembled Nanoprobe for Photoacoustic Inflammation Imaging to Assess Atherosclerotic Plaque Vulnerability

    DOI: 10.1021/acs.analchem.8b04912

    PMID: 30497260

    		 Sample: Cell culture supernatant
  73. Frontiers in Cardiovascular Medicine (2021) IF: 6.05
    Potential Mechanism of Dingji Fumai Decoction Against Atrial Fibrillation Based on Network Pharmacology, Molecular Docking, and Experimental Verification Integration Strategy

    DOI: 10.3389/fcvm.2021.712398

    PMID: 34859062

    		 Sample: HL-1 cells
  74. Frontiers in Cardiovascular Medicine (2021) IF: 6.05
    Long Non-coding RNA N1LR Protects Against Myocardial Ischemic/Reperfusion Injury Through Regulating the TGF-β Signaling Pathway

    DOI: 10.3389/fcvm.2021.654969

    PMID: 34485393

    		 Sample: serum
  75. Frontiers in Microbiology (2022) IF: 6.064
    Recombinant Listeria ivanovii strain expressing listeriolysin O in place of ivanolysin O might be a potential antigen carrier for vaccine construction

    DOI: 10.3389/fmicb.2022.962326

    PMID: 35935244

    		 Sample: splenocytes
  76. ACTA PHARMACOLOGICA SINICA (2021) IF: 6.15
    Luteolin alleviates cognitive impairment in Alzheimer’s disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation

    DOI: 10.1038/s41401-021-00702-8
    Sample: brain
  77. FREE RADICAL BIOLOGY AND MEDICINE (2020) IF: 6.17
    Dry eye induced by exposure to cigarette smoke pollution: An in vivo and in vitro study

    DOI: 10.1016/j.freeradbiomed.2020.04.007

    PMID: 32320747

    		 Sample: Cell lysate,Cell culture supernatant
  78. JOURNAL OF MEDICINAL CHEMISTRY (2020) IF: 6.205
    Small-Molecule Antagonist Targeting Exportin-1 via Rational Structure-Based Discovery

    DOI: 10.1021/acs.jmedchem.9b01663
    Sample: serum
  79. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023) IF: 6.208
    The Mechanism of Two Benzaldehydes from Aspergillus terreus C23-3 Improve Neuroinflammatory and Neuronal Damage to Delay the Progression of Alzheimer’s Disease

    DOI: 10.3390/ijms24020905
    Sample: BV-2 cell
  80. Arabian Journal of Chemistry (2023) IF: 6.212
    A pair of new enantiomeric hybrid phthalide–adenines with a rare 5-oxa-1-azaspiro[3,4]octane moiety and two pairs of new enantiomeric hybrid paraethyl phenol–adenines from Ligusticum chuanxiong

    DOI: 10.1016/j.arabjc.2023.104696
    Sample: RAW264.7 cell
  81. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2021) IF: 6.291
    Novel insights into the role of BRD4 in fine particulate matter induced airway hyperresponsiveness

    DOI: 10.1016/j.ecoenv.2021.112440

    PMID: 34175826

    		 Sample: Bronchoalveolar lavage fluid
  82. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2022) IF: 6.291
    Diet composition affects long-term zearalenone exposure on the gut–blood–liver axis metabolic dysfunction in mice

    DOI: 10.1016/j.ecoenv.2022.113466
    Sample: serum
  83. Antioxidants (2021) IF: 6.313
    Aronia melanocarpa Extract Fermented by Lactobacillus plantarum EJ2014 Modulates Immune Response in Mice

    DOI: 10.3390/antiox10081276

    PMID: 34439524

    		 Sample: plasma
  84. Food & Function (2023) IF: 6.317
    DHA-enriched phosphatidylserine alleviates high fat diet-induced jejunum injury in mice by modulating gut microbiota

    DOI: 10.1039/D2FO03019E
    Sample: serum
  85. Food & Function (2022) IF: 6.317
    DHA-enriched phosphatidylcholine from Clupea harengus roes regulates the gut–liver axis to ameliorate high-fat diet-induced non-alcoholic fatty liver disease

    DOI: 10.1039/D2FO02672D
    Sample: liver
  86. Pharmaceutics (2021) IF: 6.321
    Enhancement of Rotator Cuff Healing with Farnesol-Impregnated Gellan Gum/Hyaluronic Acid Hydrogel Membranes in a Rabbit Model

    DOI: 10.3390/pharmaceutics13070944

    PMID: 34202556

    		 Sample: C2C12 myoblasts
  87. JOURNAL OF CELLULAR PHYSIOLOGY (2021) IF: 6.384
    STING-mediated inflammation contributes to Gao binge ethanol feeding model

    DOI: 10.1002/jcp.30606

    PMID: 34698390

    		 Sample: RAW264.7 cell
  88. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021) IF: 6.514
    Design, synthesis, and biological evaluation of carbamate derivatives of N-salicyloyl tryptamine as multifunctional agents for the treatment of Alzheimer's disease

    DOI: 10.1016/j.ejmech.2021.114044

    PMID: 34923430

    		 Sample: BV2 cell
  89. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021) IF: 6.514
    Design and synthesis of 7-O-1,2,3-triazole hesperetin derivatives to relieve inflammation of acute liver injury in mice

    DOI: 10.1016/j.ejmech.2021.113162

    PMID: 33493826

    		 Sample: Cell culture supernatant
  90. BIOMEDICINE & PHARMACOTHERAPY (2019) IF: 6.53
    Inhibition of HDAC6 attenuates LPS-induced inflammation in macrophages by regulating oxidative stress and suppressing the TLR4-MAPK/NF-κB pathways

    DOI: 10.1016/j.biopha.2019.109166

    PMID: 31255993

    		 Sample: Cell culture supernatant
  91. BIOMEDICINE & PHARMACOTHERAPY (2021) IF: 6.53
    Curcumin modulates multiple cell death, matrix metalloproteinase activation and cardiac protein release in susceptible and resistant Plasmodium berghei-infected mice

    DOI: 10.1016/j.biopha.2021.112454

    PMID: 34894518

    		 Sample: serum
  92. BIOMEDICINE & PHARMACOTHERAPY (2022) IF: 6.53
    Activation of α7nAChR preserves intestinal barrier integrity by enhancing the HO-1 / STAT3 signaling to inhibit NF-κB activation in mice

    DOI: 10.1016/j.biopha.2022.112733

    PMID: 36068769

    		 Sample: Serum
  93. Oxidative Medicine and Cellular Longevity (2022) IF: 6.543
    Preventive Effect of Collagen Peptides from Acaudina molpadioides on Acute Kidney Injury through Attenuation of Oxidative Stress and Inflammation

    DOI: 10.1155/2022/8186838

    PMID: 35592533

    		 Sample: serum
  94. Oxidative Medicine and Cellular Longevity (2021) IF: 6.543
    Low-Dose Copper Exposure Exacerbates Depression-Like Behavior in ApoE4 Transgenic Mice

    DOI: 10.1155/2021/6634181

    PMID: 33833851

    		 Sample: Tissue homogenate(brains)
  95. Oxidative Medicine and Cellular Longevity (2016) IF: 6.543
    Hydrogen Sulfide Mitigates Kidney Injury in High Fat Diet-Induced Obese Mice

    DOI: 10.1155/2016/2715718
    Sample: Plasma
  96. SCIENCE OF THE TOTAL ENVIRONMENT (2020) IF: 6.551
    Exposure to hyperandrogen drives ovarian dysfunction and fibrosis by activating the NLRP3 inflammasome in mice

    DOI: 10.1016/j.scitotenv.2020.141049
    Sample: serum
  97. Frontiers in Nutrition (2022) IF: 6.576
    Using Collagen Peptides From the Skin of Monkfish (Lophius litulon) to Ameliorate Kidney Damage in High-Fat Diet Fed Mice by Regulating the Nrf2 Pathway and NLRP3 Signaling

    DOI: 10.3389/fnut.2022.798708
    Sample: kidney
  98. Frontiers in Nutrition (2022) IF: 6.59
    The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism

    DOI: 10.3389/fnut.2022.893344
    Sample: Serum
  99. Cells (2021) IF: 6.6
    Roles of Crosstalk between Astrocytes and Microglia in Triggering Neuroinflammation and Brain Edema Formation in 1,2-Dichloroethane-Intoxicated Mice

    DOI: 10.3390/cells10102647

    PMID: 34685627

    		 Sample: cerebral tissue
  100. Cells (2019) IF: 6.6
    Anti-Neuroinflammatory Effect of Alantolactone through the Suppression of the NF-κB and MAPK Signaling Pathways

    DOI: 10.3390/cells8070739
    Sample: BV2 cells
  101. PHYTOMEDICINE (2022) IF: 6.656
    Treatment of ulcerative colitis with Wu-Mei-Wan by inhibiting intestinal inflammatory response and repairing damaged intestinal mucosa

    DOI: 10.1016/j.phymed.2022.154362

    PMID: 35947900

    		 Sample: serum
  102. PHYTOMEDICINE (2022) IF: 6.656
    Total terpenoids of Inula japonica activated the Nrf2 receptor to alleviate the inflammation and oxidative stress in LPS-induced acute lung injury

    DOI: 10.1016/j.phymed.2022.154377

    PMID: 36116200

    		 Sample: lung
  103. PHYTOMEDICINE (2022) IF: 6.656
    Total flavonoids of Inula japonica alleviated the inflammatory response and oxidative stress in LPS-induced acute lung injury via inhibiting the sEH activity: Insights from lipid metabolomics

    DOI: 10.1016/j.phymed.2022.154380

    PMID: 36150346

    		 Sample: lung
  104. PHYTOMEDICINE (2022) IF: 6.656
    Integration of transdermal chemistry and network pharmacology to decipher the mechanism of ShexiangZhuifeng analgesic plaster to treat rheumatoid arthritis

    DOI: 10.1016/j.phymed.2022.154507

    PMID: 36334391

    		 Sample: RAW264.7 cells
  105. Nutrients (2022) IF: 6.706
    Cornuside Is a Potential Agent against Alzheimer’s Disease via Orchestration of Reactive Astrocytes

    DOI: 10.3390/nu14153179
    Sample: cerebral tissue,BV2 cell
  106. Journal of Inflammation Research (2021) IF: 6.922
    Histone Deacetylase 6 Regulates the Activation of M1 Macrophages by the Glycolytic Pathway During Acute Liver Failure

    DOI: 10.2147/JIR.S302391
    Sample: liver,RAW264.7 cell
  107. Journal of Inflammation Research (2022) IF: 6.922
    CD73 Attenuates Alcohol-Induced Liver Injury and Inflammation via Blocking TLR4/MyD88/NF-κB Signaling Pathway

    DOI: 10.2147/JIR.S341680
    Sample: serum,RAW264.7 cell
  108. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 6.953
    Structures and immunomodulatory activity of one galactose- and arabinose-rich polysaccharide from Sambucus adnata

    DOI: 10.1016/j.ijbiomac.2022.03.132

    PMID: 35346678

    		 Sample: RAW264.7 cell
  109. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021) IF: 6.953
    Structural characterization and immunomodulatory activities of two polysaccharides from Rehmanniae Radix Praeparata

    DOI: 10.1016/j.ijbiomac.2021.06.100

    PMID: 34197855

    		 Sample: RAW264.7 cells
  110. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021) IF: 6.953
    Nitraria tangutorum Bobr.-derived polysaccharides protect against LPS-induced lung injury

    DOI: 10.1016/j.ijbiomac.2021.06.181

    PMID: 34216671

    		 Sample: lung
  111. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022) IF: 6.953
    A monomeric polysaccharide from Polygonatum sibiricum improves cognitive functions in a model of Alzheimer's disease by reshaping the gut microbiota

    DOI: 10.1016/j.ijbiomac.2022.05.185

    PMID: 35661666

    		 Sample: intestines
  112. LIFE SCIENCES (2021) IF: 5.037
    Pancreastatin induces hepatic steatosis in type 2 diabetes by impeding mitochondrial functioning

    DOI: 10.1016/j.lfs.2021.119905

    PMID: 34453940

    		 Sample: serum
  113. LIFE SCIENCES (2020) IF: 5.037
    Fenugreek attenuates obesity-induced inflammation and improves insulin resistance through downregulation of iRhom2/TACE

    DOI: 10.1016/j.lfs.2020.118222

    PMID: 32768577

    		 Sample: Serum
  114. LIFE SCIENCES (2021) IF: 5.037
    Demethylenetetrahydroberberine alleviates nonalcoholic fatty liver disease by inhibiting the NLRP3 inflammasome and oxidative stress in mice

    DOI: 10.1016/j.lfs.2021.119778

    PMID: 34192596

    		 Sample: serum
  115. CELL PROLIFERATION (2019) IF: 5.039
    Inhibition of CREB‐mediated ZO‐1 and activation of NF‐κB‐induced IL‐6 by colonic epithelial MCT4 destroys intestinal barrier function

    DOI: 10.1111/cpr.12673
    Sample: serum
  116. Oxidative Medicine and Cellular Longevity (2020) IF: 5.076
    The Inhibition of P-Selectin Reduced Severe Acute Lung Injury in Immunocompromised Mice

    DOI: 10.1155/2020/8430465

    PMID: 32377309

    		 Sample: Serum
  117. Marine Drugs (2022) IF: 5.118
    Monkfish Peptides Mitigate High Fat Diet-Induced Hepatic Steatosis in Mice

    DOI: 10.3390/md20050312

    PMID: 35621963

    		 Sample: hepatic
  118. Marine Drugs (2022) IF: 5.118
    In Vitro and In Vivo Dendritic Cell Immune Stimulation Effect of Low Molecular Weight Fucoidan from New Zealand Undaria pinnatifida

    DOI: 10.3390/md20030197

    PMID: 35323496

    		 Sample: Dendritic cells (DCs)
  119. Food Science and Human Wellness (2022) IF: 5.154
    Selenium-enriched oolong tea (Camellia sinensis) extract exerts anti-inflammatory potential via targeting NF-κB and MAPK pathways in macrophages

    DOI: 10.1016/j.fshw.2021.12.020
    Sample: RAW264.7 cell
  120. ARTHRITIS RESEARCH & THERAPY (2021) IF: 5.156
    Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pathways

    DOI: 10.1186/s13075-021-02512-z

    PMID: 33990219

    		 Sample: Serum,Cell culture supernatant
  121. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020) IF: 5.162
    A novel polysaccharide from Acorus tatarinowii protects against LPS-induced neuroinflammation and neurotoxicity by inhibiting TLR4-mediated MyD88/NF-κB and PI3K/Akt signaling pathways

    DOI: 10.1016/j.ijbiomac.2020.06.266

    PMID: 32621930

    		 Sample: Cell culture supernatant
  122. Arabian Journal of Chemistry (2022) IF: 5.165
    Size, surface charge and flexibility of vinegar-baked Radix Bupleuri polysaccharide affecting the immune response

    DOI: 10.1016/j.arabjc.2022.104008
    Sample: RAW264.7 cell
  123. Oncotarget (2017) IF: 5.168
    Regulatory role of NKG2D+ NK cells in intestinal lamina propria by secreting double-edged Th1 cytokines in ulcerative colitis

    DOI: 10.18632/oncotarget.22132
    Sample: Tissue homogenate
  124. Oncotarget (2017) IF: 5.168
    Glioblastoma progression is assisted by induction of immunosuppressive function of pericytes through interaction with tumor cells

    DOI: 10.18632/oncotarget.19804
    Sample: Cell culture supernatant
  125. FASEB JOURNAL (2021) IF: 5.192
    Emodin inhibits lipid accumulation and inflammation in adipose tissue of high-fat diet-fed mice by inducing M2 polarization of adipose tissue macrophages

    DOI: 10.1096/fj.202100157RR

    PMID: 34110631

    		 Sample: serum,macrophage cells
  126. JOURNAL OF ETHNOPHARMACOLOGY (2022) IF: 5.195
    The dichloromethane extract of Callicarpa longissima rich in diterpenoid phenols exerts anti-inflammatory effect via inhibiting the TLR4/NF-κB signaling pathway

    DOI: 10.1016/j.jep.2022.116124
    Sample: RAW264.7 cells
  127. EUROPEAN JOURNAL OF PHARMACOLOGY (2022) IF: 5.195
    Orally administered MOTS-c analogue ameliorates dextran sulfate sodium-induced colitis by inhibiting inflammation and apoptosis

    DOI: 10.1016/j.ejphar.2022.175469
    Sample: plasma
  128. JOURNAL OF ETHNOPHARMACOLOGY (2022) IF: 5.195
    Lian-Qu formula treats metabolic syndrome via reducing fat synthesis, insulin resistance and inflammation

    DOI: 10.1016/j.jep.2022.116060
    Sample: serum
  129. Journal of Functional Foods (2022) IF: 5.223
    High fiber multigrain supplementation improved disease activity score, circulating inflammatory and oxidative stress biomarkers in rheumatoid arthritis (RA) patients: A randomized human clinical trial

    DOI: 10.1016/j.jff.2022.105392
    Sample: blood
  130. CLINICAL SCIENCE (2020) IF: 5.223
    DNMT3b-mediated methylation of ZSWIM3 enhances inflammation in alcohol-induced liver injury via regulating TRAF2-mediated NF-κB pathway

    DOI: 10.1042/CS20200031
    Sample: RAW264.7 cell
  131. CNS Neuroscience & Therapeutics (2022) IF: 5.243
    Inhibition of phosphodiesterase-4 in the spinal dorsal horn ameliorates neuropathic pain via cAMP-cytokine-Cx43 signaling in mice

    DOI: 10.1111/cns.13807
    Sample: spinal cord
  132. NEUROPHARMACOLOGY (2022) IF: 5.251
    PEA-OXA ameliorates allodynia, neuropsychiatric and adipose tissue remodeling induced by social isolation

    DOI: 10.1016/j.neuropharm.2022.108978

    PMID: 35157898

    		 Sample: Mesenchymal stromal cells (MSCs)
  133. BIOORGANIC CHEMISTRY (2022) IF: 5.275
    Twelve novel sesquiterpenes with anti-inflammatory and cholesterol-lowering activities from burdock leaves

    DOI: 10.1016/j.bioorg.2022.105940

    PMID: 35749853

    		 Sample: RAW264.7 cell
  134. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021) IF: 5.279
    Probiotic Bacillus cereus Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice through Improvement of the Intestinal Barrier Function, Anti-Inflammation, and Gut Microbiota Modulation

    DOI: 10.1021/acs.jafc.1c03375

    PMID: 34677958

    		 Sample: colon tissue
  135. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2022) IF: 5.279
    Laminaria japonica Polysaccharide Suppresses Atherosclerosis via Regulating Autophagy-Mediated Macrophage Polarization

    DOI: 10.1021/acs.jafc.1c07483

    PMID: 35167294

    		 Sample: aortic,Raw264.7 cell
  136. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2022) IF: 5.279
    Industrially Produced Rice Protein Ameliorates Dextran Sulfate Sodium-Induced Colitis via Protecting the Intestinal Barrier, Mitigating Oxidative Stress, and Regulating Gut Microbiota

    DOI: 10.1021/acs.jafc.2c00585
    Sample: Colon tissue
  137. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021) IF: 5.279
    Algal Oil Rich in Docosahexaenoic Acid Alleviates Intestinal Inflammation Induced by Antibiotics Associated with the Modulation of the Gut Microbiome and Metabolome

    DOI: 10.1021/acs.jafc.0c07323

    PMID: 33900083

    		 Sample: Tissue homogenate(colon)
  138. Frontiers in Cellular and Infection Microbiology (2021) IF: 5.293
    Fecal Microbiota Transplantation Protects the Intestinal Mucosal Barrier by Reconstructing the Gut Microbiota in a Murine Model of Sepsis

    DOI: 10.3389/fcimb.2021.736204
    Sample: serum
  139. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2022) IF: 5.295
    Up-regulation of the human-specific CHRFAM7A gene protects against renal fibrosis in mice with obstructive nephropathy

    DOI: 10.1111/jcmm.17630
    Sample: serum
  140. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2022) IF: 5.295
    Osteocytic cells exposed to titanium particles increase sclerostin expression and inhibit osteoblastic cell differentiation mostly via direct cell-to-cell contact

    DOI: 10.1111/jcmm.17460

    PMID: 35762300

    		 Sample: MLO-Y4 cell,MC3T3-E1cell
  141. BIOORGANIC CHEMISTRY (2022) IF: 5.307
    Synthesis of mitochondria-targeted ferulic acid amide derivatives with antioxidant, anti-inflammatory activities and inducing mitophagy

    DOI: 10.1016/j.bioorg.2022.106037

    PMID: 35863132

    		 Sample: RAW264.7 cell
  142. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021) IF: 5.31
    Verapamil inhibits early acute liver failure through suppressing the NLRP3 inflammasome pathway

    DOI: 10.1111/jcmm.16357

    PMID: 34031983

    		 Sample: Tissue homogenate
  143. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021) IF: 5.31
    Pseudolaric acid B ameliorates synovial inflammation and vessel formation by stabilizing PPARγ to inhibit NF-κB signalling pathway

    DOI: 10.1111/jcmm.16670

    PMID: 34117708

    		 Sample: Raw 264.7 cells
  144. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021) IF: 5.31
    Oxidized high-density lipoprotein enhances endocrine disorders and ovarian damage in rats

    DOI: 10.1111/jcmm.16197

    PMID: 34346538

    		 Sample: granulosa cells (GCs)
  145. Food Bioscience (2023) IF: 5.318
    A comparative study of fermented buffalo and camel milk with anti-inflammatory, ACE-inhibitory and anti-diabetic properties and release of bio active peptides with molecular interactions: In vitro, in silico and molecular study

    DOI: 10.1016/j.fbio.2023.102373
    Sample: RAW 264.7 cell
  146. PHYTOMEDICINE (2021) IF: 5.34
    Bioactive constituents of Mosla chinensis-cv. Jiangxiangru ameliorate inflammation through MAPK signaling pathways and modify intestinal microbiota in DSS-induced colitis mice

    DOI: 10.1016/j.phymed.2021.153804

    PMID: 34735907

    		 Sample: colon tissue
  147. Food & Function (2022) IF: 5.396
    Combined royal jelly 10-hydroxydecanoic acid and aspirin has a synergistic effect against memory deficit and neuroinflammation

    DOI: 10.1039/D1FO02397G

    PMID: 35142767

    		 Sample: BV-2 cell
  148. Food & Function (2022) IF: 5.396
    Bioactivity-guided isolation of the major anthocyanin from Lycium ruthenicum Murr. fruit and its antioxidant activity and neuroprotective effects in vitro and in vivo

    DOI: 10.1039/D1FO04095B

    PMID: 35233585

    		 Sample: hippocampus
  149. Food & Function (2021) IF: 5.396
    Bioactives and their metabolites from Tetrastigma hemsleyanum leaves ameliorate DSS-induced colitis via protecting intestinal barrier, mitigating oxidative stress and regulating gut microbiota

    DOI: 10.1039/D1FO02588K
    Sample: colon tissue
  150. Food & Function (2022) IF: 5.396
    Astilbin from Smilax glabra Roxb. alleviates high-fat diet-induced metabolic dysfunction

    DOI: 10.1039/D2FO00060A

    PMID: 35388843

    		 Sample: serum
  151. Chinese Medicine (2022) IF: 5.455
    Anti-inflammatory effects of anemonin on acute ulcerative colitis via targeted regulation of protein kinase C-θ

    DOI: 10.1186/s13020-022-00599-3

    PMID: 35346284

    		 Sample: colon tissues
  152. Journal of Ginseng Research (2020) IF: 5.487
    Inhibitory activity of gintonin on inflammation in human IL-1β-stimulated fibroblast-like synoviocytes and collagen-induced arthritis in mice

    DOI: 10.1016/j.jgr.2020.12.001

    PMID: 34295211

    		 Sample: serum
  153. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018) IF: 5.5
    The Effects of Angelica Sinensis Polysaccharide on Tumor Growth and Iron Metabolism by Regulating Hepcidin in Tumor-Bearing Mice

    DOI: 10.1159/000490185
    Sample: Serum
  154. Foods (2022) IF: 5.561
    Encapsulation of Functional Plant Oil by Spray Drying: Physicochemical Characterization and Enhanced Anti-Colitis Activity

    DOI: 10.3390/foods11192993

    PMID: 36230069

    		 Sample: serum
  155. FOOD AND CHEMICAL TOXICOLOGY (2023) IF: 5.572
    Maternal exposure to a glyphosate-based herbicide impairs placental development through endoplasmic reticulum stress in mice

    DOI: 10.1016/j.fct.2023.113640
    Sample: Placental tissue
  156. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020) IF: 5.573
    Melatonin Derivatives Combat with Inflammation-related Cancer by Targeting the Main Culprit STAT3

    DOI: 10.1016/j.ejmech.2020.113027

    PMID: 33248852

    		 Sample: Cell culture supernatant
  157. MOLECULAR NEUROBIOLOGY (2022) IF: 5.59
    Selective GSK3β Inhibition Mediates an Nrf2-Independent Anti-inflammatory Microglial Response

    DOI: 10.1007/s12035-022-02923-2

    PMID: 35739410

    		 Sample: SIM-A9 cell
  158. EUROPEAN JOURNAL OF NUTRITION (2021) IF: 5.619
    Broccoli microgreens juice reduces body weight by enhancing insulin sensitivity and modulating gut microbiota in high-fat diet-induced C57BL/6J obese mice

    DOI: 10.1007/s00394-021-02553-9

    PMID: 33866422

    		 Sample: Serum
  159. Frontiers in Molecular Neuroscience (2019) IF: 5.639
    Corilagin Interferes With Toll-Like Receptor 3-Mediated Immune Response in Herpes Simplex Encephalitis

    DOI: 10.3389/fnmol.2019.00083
    Sample: brain tissues,BV-2 cells
  160. FREE RADICAL BIOLOGY AND MEDICINE (2019) IF: 5.657
    Oral administration of 3,3′-diselenodipropionic acid prevents thoracic radiation induced pneumonitis in mice by suppressing NF-kB/IL-17/G-CSF/neutrophil axis

    DOI: 10.1016/j.freeradbiomed.2019.09.009
    Sample: Bronchoalveolar Lavage Fluid,Tissue homogenate
  161. Aging-US (2021) IF: 5.682
    Investigating the mechanisms of Modified Xiaoyaosan (tiaogan-liqi prescription) in suppressing the progression of atherosclerosis, by means of integrative pharmacology and experimental validation

    DOI: 10.18632/aging.202832

    PMID: 33839698

    		 Sample: Plasma
  162. Aging-US (2021) IF: 5.682
    CHIP ameliorates cerebral ischemia-reperfusion injury by attenuating necroptosis and inflammation

    DOI: 10.18632/aging.203774

    PMID: 34905731

    		 Sample: brain
  163. MOLECULAR NEUROBIOLOGY (2022) IF: 5.682
    Activation of Angiotensin-converting Enzyme 2 Protects Against Lipopolysaccharide-induced Glial Activation by Modulating Angiotensin-converting Enzyme 2/Angiotensin (1–7)/Mas Receptor Axis

    DOI: 10.1007/s12035-022-03061-5
    Sample: BV2 cell
  164. Journal of Neuroinflammation (2019) IF: 5.7
    Baicalin ameliorates neuroinflammation-induced depressive-like behavior through inhibition of toll-like receptor 4 expression via the PI3K/AKT/FoxO1 pathway

    DOI: 10.1186/s12974-019-1474-8
    Sample: hippocampus tissue,BV2 cells,primary microglia cel
  165. INTERNATIONAL IMMUNOPHARMACOLOGY (2023) IF: 5.714
    C1q/tumor necrosis factor-related protein-6 exerts protective effects on myocardial ischemia–reperfusion injury through the modulation of the Akt-GSK-3β-Nrf2 signaling cascade

    DOI: 10.1016/j.intimp.2023.109678
    Sample: cardiac muscle tissues,cardiomyocytes
  166. Nutrients (2022) IF: 5.719
    Friedelin Alleviates the Pathogenesis of Collagenase-Induced Tendinopathy in Mice by Promoting the Selective Autophagic Degradation of p65

    DOI: 10.3390/nu14081673

    PMID: 35458235

    		 Sample: serum,tenocytes
  167. Journal of Neuroinflammation (2020) IF: 5.793
    Systemic exosomal miR-193b-3p delivery attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage in mice

    DOI: 10.1186/s12974-020-01745-0
    Sample: brain
  168. Frontiers in Pharmacology (2022) IF: 5.811
    Wu-Mei-Wan Ameliorates Murine Ulcerative Colitis by Regulating Macrophage Polarization

    DOI: 10.3389/fphar.2022.859167

    PMID: 35387334

    		 Sample: Serum
  169. Frontiers in Pharmacology (2022) IF: 5.811
    The Effect of Shionone on Sepsis-Induced Acute Lung Injury by the ECM1/STAT5/NF-κB Pathway

    DOI: 10.3389/fphar.2021.764247
    Sample: serum,RAW264.7 cell
  170. Frontiers in Pharmacology (2022) IF: 5.811
    Naringin Interferes Doxorubicin-Induced Myocardial Injury by Promoting the Expression of ECHS1

    DOI: 10.3389/fphar.2022.859755

    PMID: 35496302

    		 Sample: heart tissue
  171. Frontiers in Pharmacology (2021) IF: 5.811
    Excessive Intake of Longan Arillus Alters gut Homeostasis and Aggravates Colitis in Mice

    DOI: 10.3389/fphar.2021.640417

    PMID: 33841158

    		 Sample: Serum
  172. Frontiers in Pharmacology (2021) IF: 5.811
    Ethyl 2-Succinate-Anthraquinone Attenuates Inflammatory Response and Oxidative Stress via Regulating NLRP3 Signaling Pathway.

    DOI: 10.3389/fphar.2021.719822
    Sample: blood
  173. Frontiers in Pharmacology (2018) IF: 5.811
    Emodin Attenuates Lipopolysaccharide-Induced Acute Liver Injury via Inhibiting the TLR4 Signaling Pathway in vitro and in vivo

    DOI: 10.3389/fphar.2018.00962
    Sample: Cell culture supernatant
  174. GLIA (2019) IF: 5.829
    Activation of G protein‐coupled receptor 30 protects neurons by regulating autophagy in astrocytes

    DOI: 10.1002/glia.23697
    Sample: astrocytes
  175. BIOCHEMICAL PHARMACOLOGY (2022) IF: 5.858
    Tuftsin ameliorates splenic inflammatory injury by promoting neuropilin-1 in severe acute pancreatitis

    DOI: 10.1016/j.bcp.2022.115030

    PMID: 35381211

    		 Sample: serum
  176. INTERNATIONAL JOURNAL OF PHARMACEUTICS (2022) IF: 5.875
    Inflammation-targeted sialic acid-dexamethasone conjugates for reducing the side effects of glucocorticoids

    DOI: 10.1016/j.ijpharm.2022.121900

    PMID: 35690305

    		 Sample: kidney
  177. PHYTOTHERAPY RESEARCH (2022) IF: 5.882
    Nimbolide attenuates gut dysbiosis and prevents bacterial translocation by improving intestinal barrier integrity and ameliorating inflammation in hepatocellular carcinoma

    DOI: 10.1002/ptr.7434

    PMID: 35229912

    		 Sample: plasma
  178. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2022) IF: 5.895
    Rice Protein Peptides Alleviate Dextran Sulfate Sodium-Induced Colitis via the Keap1–Nrf2 Signaling Pathway and Regulating Gut Microbiota

    DOI: 10.1021/acs.jafc.2c04862
    Sample: colon tissue
  179. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021) IF: 5.924
    Farnesol-Loaded Liposomes Protect the Epidermis and Dermis from PM2.5-Induced Cutaneous Injury

    DOI: 10.3390/ijms22116076
    Sample: L929 fibroblasts cells
  180. ANTIVIRAL RESEARCH (2019) IF: 5.97
    N-Acetyl cysteine effectively alleviates Coxsackievirus B-Induced myocarditis through suppressing viral replication and inflammatory response

    DOI: 10.1016/j.antiviral.2019.104699
    Sample: heart
  181. Frontiers in Pharmacology (2022) IF: 5.988
    MiR-146b-5p/TRAF6 axis is essential for Ginkgo biloba L. extract GBE to attenuate LPS-induced neuroinflammation

    DOI: 10.3389/fphar.2022.978587

    PMID: 36091773

    		 Sample: BV-2 cell
  182. Frontiers in Pharmacology (2022) IF: 5.988
    Midazolam Ameliorates Acute Liver Injury Induced by Carbon Tetrachloride via Enhancing Nrf2 Signaling Pathway

    DOI: 10.3389/fphar.2022.940137

    PMID: 35873576

    		 Sample: liver
  183. Frontiers in Pharmacology (2022) IF: 5.988
    Metformin Improves the Senescence of Renal Tubular Epithelial Cells in a High-Glucose State Through E2F1

    DOI: 10.3389/fphar.2022.926211

    PMID: 35814218

    		 Sample: renal cortical
  184. Frontiers in Aging Neuroscience (2015) IF: 4
    PGC-1 silencing compounds the perturbation of mitochondrial function caused by mutant SOD1 in skeletal muscle of ALS mouse model

    DOI: 10.3389/fnagi.2015.00204
    Sample: Serum
  185. Frontiers in Microbiology (2018) IF: 4.019
    The Influence of Acanthamoeba–Legionella Interaction in the Virulence of Two Different Legionella Species

    DOI: 10.3389/fmicb.2018.02962
    Sample: Cell culture supernatant
  186. JOURNAL OF NATURAL PRODUCTS (2022) IF: 4.05
    A Natural Plant Ingredient, Menthone, Regulates T Cell Subtypes and Lowers Pro-inflammatory Cytokines of Rheumatoid Arthritis

    DOI: 10.1021/acs.jnatprod.1c01231

    PMID: 35302365

    		 Sample: blood
  187. American Journal of Translational Research (2019) IF: 4.06
    Xiaoyaosan prevents atherosclerotic vulnerable plaque formation through heat shock protein/glucocorticoid receptor axis-mediated mechanism

    PMID: 31632527

    		 Sample: serum
  188. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2019) IF: 4.067
    Ameliorative effects of snake (Deinagkistrodon acutus) oil and its main fatty acids against UVB-induced skin photodamage in mice

    DOI: 10.1016/j.jphotobiol.2019.111538
    Sample: skin
  189. CARBOHYDRATE POLYMERS (2015) IF: 4.074
    Structural analysis and immunoregulation activity comparison of five polysaccharides from Angelica sinensis

    DOI: 10.1016/j.carbpol.2015.12.050
    Sample: Cell culture supernatant
  190. BRAIN RESEARCH BULLETIN (2021) IF: 4.079
    Sesamin suppresses advanced glycation end products induced microglial reactivity using BV2 microglial cell line as a model

    DOI: 10.1016/j.brainresbull.2021.04.012

    PMID: 33894297

    		 Sample: Cell culture medium
  191. BRAIN RESEARCH BULLETIN (2021) IF: 4.079
    Geniposide protects depression through BTK/JAK2/STAT1 signaling pathway in lipopolysaccharide-induced depressive mice

    DOI: 10.1016/j.brainresbull.2021.02.008

    PMID: 33561536

    		 Sample: Serum,Cell culture supernatant,Tissue homogenate
  192. BIOCHIMIE (2021) IF: 4.079
    Ex vivo tolerization and M2 polarization of macrophages dampens both pro- and anti-inflammatory cytokine production in response to diabetic wound fluid stimulation

    DOI: 10.1016/j.biochi.2021.12.009
    Sample: wound fluid,J774A.1 monocytic cell
  193. BIOLOGICAL TRACE ELEMENT RESEARCH (2022) IF: 4.081
    Selenium Supplementation Protects Against Arsenic-Trioxide-Induced Cardiotoxicity Via Reducing Oxidative Stress and Inflammation Through Increasing NAD+ Pool

    DOI: 10.1007/s12011-022-03478-y
    Sample: heart tissue
  194. PHYTOTHERAPY RESEARCH (2020) IF: 4.087
    The effect of geniposide on chronic unpredictable mild stress‐induced depressive mice through BTK/TLR4/NF‐κB and BDNF/TrkB signaling pathways

    DOI: 10.1002/ptr.6846
    Sample: Serum,Tissue homogenate,Cell culture supernatant
  195. Foods (2020) IF: 4.092
    Protective Effect of Prunus mume Fermented with Mixed Lactic Acid Bacteria in Dextran Sodium Sulfate-Induced Colitis

    DOI: 10.3390/foods10010058

    PMID: 33383792

    		 Sample: colon tissue,serum
  196. INFLAMMATION (2022) IF: 4.092
    Cannabinoid Analogue WIN 55212–2 Protects Paraquat-Induced Lung Injury and Enhances Macrophage M2 Polarization

    DOI: 10.1007/s10753-022-01688-z
    Sample: BALF
  197. INFLAMMATION (2021) IF: 4.092
    Benzoylaconine Modulates LPS-Induced Responses Through Inhibition of Toll-Like Receptor-Mediated NF-κB and MAPK Signaling in RAW264.7 Cells

    DOI: 10.1007/s10753-021-01478-z
    Sample: RAW264.7 cells
  198. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2021) IF: 4.101
    FXII regulates the formation of deep vein thrombosis via the PI3K/AKT signaling pathway in mice

    DOI: 10.3892/ijmm.2021.4920

    PMID: 33760144

    		 Sample: femoral vein tissue,plasma
  199. ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
    Upregulation of FAM129B protects cardiomyocytes from hypoxia/reoxygenation-induced injury by inhibiting apoptosis, oxidative stress, and inflammatory response via enhancing Nrf2/ARE activation

    DOI: 10.1002/tox.23461

    PMID: 34995000

    		 Sample: cardiomyocytes
  200. ENVIRONMENTAL TOXICOLOGY (2021) IF: 4.119
    Inhibition of USP15 ameliorates high-glucose-induced oxidative stress and inflammatory injury in podocytes through regulation of the Keap1/Nrf2 signaling

    DOI: 10.1002/tox.23441

    PMID: 34931430

    		 Sample: MPC5 cell
  201. ENVIRONMENTAL TOXICOLOGY (2021) IF: 4.119
    Effects of 2,4-dichlorophenoxyacetic acid on the expression of NLRP3 inflammasome and autophagy-related proteins as well as the protective effect of Lycium barbarum polysaccharide in neonatal rats

    DOI: 10.1002/tox.23358

    PMID: 34464015

    		 Sample: BV2 cell
  202. ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
    C1q/tumor necrosis factor-related protein 9 protects cultured chondrocytes from IL-1β-induced inflammatory injury by inhibiting NLRP3 inflammasome activation via the AdipoR1/AMPK axis

    DOI: 10.1002/tox.23452

    PMID: 34990072

    		 Sample: chondrocytes
  203. ENVIRONMENTAL TOXICOLOGY (2022) IF: 4.119
    2,4-dichlorophenoxyacetic acid induces ROS activation in NLRP3 inflammatory body-induced autophagy disorder in microglia and the protective effect of Lycium barbarum polysaccharide

    DOI: 10.1002/tox.23471

    PMID: 35099110

    		 Sample: BV2 cell
  204. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2023) IF: 4.125
    Preventive effect of tilapia skin collagen hydrolysates on ulcerative colitis mice based on metabonomic and 16S rRNA gene sequencing

    DOI: 10.1002/jsfa.12457
    Sample: serum
  205. Drug Design Development and Therapy (2022) IF: 4.162
    Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics

    DOI: 10.2147/DDDT.S351092

    PMID: 35698653

    		 Sample: liver
  206. Nutrients (2019) IF: 4.171
    The Preventive and Curative Effects of Lactobacillus reuteri NK33 and Bifidobacterium adolescentis NK98 on Immobilization Stress-Induced Anxiety/Depression and Colitis in Mice

    DOI: 10.3390/nu11040819
    Sample: blood,BV-2 cells
  207. Food & Function (2020) IF: 4.171
    Polyphenol rich extracts of finger millet and kodo millet ameliorate high fat diet-induced metabolic alterations

    DOI: 10.1039/D0FO01643H

    PMID: 33089852

    		 Sample: Cell culture supernatant
  208. Food & Function (2020) IF: 4.171
    Flaxseed oligosaccharides alleviate DSS-induced colitis through modulation of gut microbiota and repair of the intestinal barrier in mice

    DOI: 10.1039/D0FO01105C

    PMID: 32856645

    		 Sample: Serum,Tissue homogenate
  209. Food & Function (2020) IF: 4.171
    Akebia trifoliata pericarp extract ameliorates inflammation through NF-κB/MAPK signaling pathways and modifies gut microbiota

    DOI: 10.1039/C9FO02917F
    Sample: colon tissue
  210. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019) IF: 4.183
    Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways

    DOI: 10.3390/ijms20051103

    PMID: 30836660

    		 Sample: Serum
  211. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019) IF: 4.183
    Resveratrol Plays a Protective Role against Premature Ovarian Failure and Prompts Female Germline Stem Cell Survival

    DOI: 10.3390/ijms20143605

    PMID: 31340581

    		 Sample: Serum,Cell culture supernatant
  212. Microbial Cell Factories (2020) IF: 4.187
    A probiotic treatment increases the immune response induced by the nasal delivery of spore-adsorbed TTFC

    DOI: 10.1186/s12934-020-01308-1

    PMID: 32075660

    		 Sample: Cell culture supernatant
  213. Transboundary and Emerging Diseases (2020) IF: 4.188
    H5N1 avian influenza virus without 80–84 amino acid deletion at the NS1 protein hijacks the innate immune system of dendritic cells for an enhanced mammalian pathogenicity

    DOI: 10.1111/tbed.13904
    Sample: Cell culture supernatant
  214. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020) IF: 4.192
    Novel Biomedical Functions of Surfactin A from Bacillus subtilis in Wound Healing Promotion and Scar Inhibition

    DOI: 10.1021/acs.jafc.0c01658

    PMID: 32412748

    		 Sample: Cell culture supernatant
  215. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020) IF: 4.192
    Modulation of Gut Microbiota by Fucoxanthin During Alleviation of Obesity in High-Fat Diet-Fed Mice

    DOI: 10.1021/acs.jafc.0c01467

    PMID: 32309947

    		 Sample: Serum,Tissue homogenate
  216. TOXICOLOGY (2021) IF: 4.221
    O-alkyl and o-benzyl hesperetin derivative-1L attenuates inflammation and protects against alcoholic liver injury via inhibition of BRD2-NF-κB signaling pathway

    DOI: 10.1016/j.tox.2021.153087

    PMID: 34974135

    		 Sample: serum,RAW264.7 cell
  217. Frontiers in Pharmacology (2020) IF: 4.225
    TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation

    DOI: 10.3389/fphar.2020.00010
    Sample: serum
  218. Frontiers in Pharmacology (2020) IF: 4.225
    Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.

    DOI: 10.3389/fphar.2020.550955
    Sample: Tissue Slice
  219. CELLULAR AND MOLECULAR NEUROBIOLOGY (2022) IF: 4.231
    Pulsed Electromagnetic Fields Protect Against Brain Ischemia by Modulating the Astrocytic Cholinergic Anti-inflammatory Pathway

    DOI: 10.1007/s10571-022-01251-2

    PMID: 35831547

    		 Sample: brain tissue,primary astrocytes
  220. Frontiers in Microbiology (2020) IF: 4.236
    Algal Oil Rich in n-3 PUFA Alleviates DSS-Induced Colitis via Regulation of Gut Microbiota and Restoration of Intestinal Barrier

    DOI: 10.3389/fmicb.2020.615404
    Sample: serum
  221. Food Bioscience (2022) IF: 4.24
    Exploring the potential of Lactobacillus and Saccharomyces for biofunctionalities and the release of bioactive peptides from whey protein fermentate

    DOI: 10.1016/j.fbio.2022.101758
    Sample: RAW264.7 cell
  222. Food Bioscience (2021) IF: 4.24
    Exploring potentials of antioxidative, anti-inflammatory activities and production of bioactive peptides in lactic fermented camel milk

    DOI: 10.1016/j.fbio.2021.101404
    Sample: RAW 264.7 cell
  223. Food Bioscience (2022) IF: 4.24
    Antioxidative, antimicrobial and anti-inflammatory activities and release of ultra-filtered antioxidative and antimicrobial peptides during fermentation of sheep milk: In-vitro, in-silico and molecular interaction studies

    DOI: 10.1016/j.fbio.2022.101666
    Sample: RAW 264.7 murine macrophage cell
  224. Scientific Reports (2017) IF: 4.259
    Glycyrrhiza uralensis water extract enhances dendritic cell maturation and antitumor efficacy of HPV dendritic cell-based vaccine

    DOI: 10.1038/srep43796
    Sample: Cell culture supernatant
  225. INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY (2022) IF: 4.286
    Identification and molecular mechanisms of novel antioxidative peptides from fermented camel milk (Kachchi breed, India) with anti-inflammatory activity in raw macrophages cell lines

    DOI: 10.1111/1471-0307.12911
    Sample: RAW 264.7 cells
  226. INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY (2022) IF: 4.286
    Antidiabetic, angiotensin-converting enzyme inhibitory and anti-inflammatory activities of fermented camel milk and characterisation of novel bioactive peptides from lactic-fermented camel milk with molecular interaction study

    DOI: 10.1111/1471-0307.12910
    Sample: RAW 264.7 cell
  227. International Journal of Nanomedicine (2016) IF: 4.32
    Effects of silver nanoparticles in combination with antibiotics on the resistant bacteria Acinetobacter baumannii

    DOI: 10.2147/IJN.S104166
    Sample: Plasma
  228. Foods (2021) IF: 4.35
    Green Pea (Pisum sativum L.) Hull Polyphenol Extracts Ameliorate DSS-Induced Colitis through Keap1/Nrf2 Pathway and Gut Microbiota Modulation

    DOI: 10.3390/foods10112765
    Sample: colon
  229. DRUG DEVELOPMENT RESEARCH (2021) IF: 4.36
    Tanshinol alleviates ulcerative colitis by promoting the expression of VLDLR

    DOI: 10.1002/ddr.21840

    PMID: 34145621

    		 Sample: colon
  230. JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36
    In vitro and in vivo relaxation and anti-inflammation of natural flavonoids from Elaeagnus pungens leaf via L-type calcium channel and targeting MAPK signal pathway

    DOI: 10.1016/j.jep.2021.114071

    PMID: 33831464

    		 Sample: Cell culture supernatant
  231. JOURNAL OF ETHNOPHARMACOLOGY (2021) IF: 4.36
    Danggui Buxue Decoction enhances the anticancer activity of gemcitabine and alleviates gemcitabine-induced myelosuppression

    DOI: 10.1016/j.jep.2021.113965

    PMID: 33639205

    		 Sample: Serum,Tissue(spleen)
  232. NEUROPHARMACOLOGY (2019) IF: 4.367
    Modulation of LPA1 receptor-mediated neuronal apoptosis by Saikosaponin-d: A target involved in depression

    DOI: 10.1016/j.neuropharm.2019.05.027
    Sample: hippocampus tissue
  233. TOXICOLOGY LETTERS (2022) IF: 4.374
    Adenosine receptor A2B mediates alcoholic hepatitis by regulating cAMP levels and the NF-KB pathway

    DOI: 10.1016/j.toxlet.2022.01.012

    PMID: 35143882

    		 Sample: serum,RAW264.7 cell
  234. Scientific Reports (2021) IF: 4.38
    The protective effect of the PDE-4 inhibitor rolipram on intracerebral haemorrhage is associated with the cAMP/AMPK/SIRT1 pathway

    DOI: 10.1038/s41598-021-98743-w

    PMID: 34611179

    		 Sample: Brain tissue
  235. Scientific Reports (2021) IF: 4.38
    Studies on the mitochondrial, immunological and inflammatory effects of solvent fractions of Diospyros mespiliformis Hochst in Plasmodium berghei-infected mice

    DOI: 10.1038/s41598-021-85790-6

    PMID: 33767260

    		 Sample: Serum
  236. Scientific Reports (2022) IF: 4.38
    Mebendazole, an anti-helminth drug, suppresses inflammation, oxidative stress and injury in a mouse model of ulcerative colitis

    DOI: 10.1038/s41598-022-14420-6

    PMID: 35715495

    		 Sample: colon tissue
  237. Scientific Reports (2021) IF: 4.38
    Hepatoprotective effect of Thymus vulgaris extract on sodium nitrite-induced changes in oxidative stress, antioxidant and inflammatory marker expression

    DOI: 10.1038/s41598-021-85264-9

    PMID: 33707592

    		 Sample: Serum
  238. COLLOIDS AND SURFACES B-BIOINTERFACES (2020) IF: 4.389
    Virus-like hollow mesoporous silica nanoparticles for cancer combination therapy

    DOI: 10.1016/j.colsurfb.2020.111452

    PMID: 33189035

    		 Sample: Serum
  239. JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2021) IF: 4.399
    Attenuation of virulence in multiple serotypes (M1, M3, and M28) of Group A Streptococcus after the loss of secreted esterase

    DOI: 10.1016/j.jmii.2021.09.008

    PMID: 34674958

    		 Sample: skin lesion
  240. MOLECULAR IMMUNOLOGY (2022) IF: 4.407
    The therapeutic potential of chondroitin sulfate in Aspergillus fumigatus keratitis

    DOI: 10.1016/j.molimm.2022.04.007

    PMID: 35504058

    		 Sample: corneas,RAW 264.7 cell
  241. MOLECULAR IMMUNOLOGY (2021) IF: 4.407
    Activation of TLR4 induces severe acute pancreatitis-associated spleen injury via ROS-disrupted mitophagy pathway

    DOI: 10.1016/j.molimm.2021.12.012

    PMID: 34965485

    		 Sample: serum,spleen tissue
  242. MOLECULES (2022) IF: 4.412
    The Expression and Bioinformatics Analysis of Circular RNAs in Endometritis Mouse Uterus Tissues

    DOI: 10.3390/molecules27123682

    PMID: 35744807

    		 Sample: uterine tissue
  243. MOLECULES (2022) IF: 4.412
    Study of the Osteoimmunomodulatory Properties of Curcumin-Modified Copper-Bearing Titanium

    DOI: 10.3390/molecules27103205

    PMID: 35630685

    		 Sample: RAW 264.7 cell
  244. MOLECULES (2021) IF: 4.412
    Rosmanol and Carnosol Synergistically Alleviate Rheumatoid Arthritis through Inhibiting TLR4/NF-κB/MAPK Pathway

    DOI: 10.3390/molecules27010078
    Sample: serum
  245. NEUROCHEMICAL RESEARCH (2022) IF: 4.414
    The protective effect of Palmatine on depressive like behavior by modulating microglia polarization in LPS-induced mice

    DOI: 10.1007/s11064-022-03672-3

    PMID: 35917005

    		 Sample: hippocampus,BV2 cell
  246. ACS Chemical Neuroscience (2021) IF: 4.418
    Peripheral Administration of a Cell-Penetrating MOTS-c Analogue Enhances Memory and Attenuates Aβ1–42- or LPS-Induced Memory Impairment through Inhibiting Neuroinflammation

    DOI: 10.1021/acschemneuro.0c00782
    Sample: Tissue homogenate(hippocampus)
  247. NEUROPHARMACOLOGY (2020) IF: 4.431
    Seizure-induced neuroinflammation contributes to ectopic neurogenesis and aggressive behavior in pilocarpine-induced status epilepticus mice

    DOI: 10.1016/j.neuropharm.2020.108044

    PMID: 32179291

    		 Sample: Cell lysate
  248. EUROPEAN JOURNAL OF PHARMACOLOGY (2022) IF: 4.432
    Research on the effect and underlying molecular mechanism of Cangzhu in the treatment of gouty arthritis

    DOI: 10.1016/j.ejphar.2022.175044
    Sample: RAW264.7-cell
  249. EUROPEAN JOURNAL OF PHARMACOLOGY (2022) IF: 4.432
    Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A

    DOI: 10.1016/j.ejphar.2022.174749

    PMID: 35007522

    		 Sample: serum
  250. Journal of Functional Foods (2021) IF: 4.451
    Structural characterization and immunomodulatory activity of a glucan from Radix Codonopsis

    DOI: 10.1016/j.jff.2021.104537
    Sample: Cell culture supernatant
  251. Journal of Functional Foods (2021) IF: 4.451
    N-acetyl-chitooligosaccharide attenuates inflammatory responses by suppression of NF-κB signaling, MAPK and NLRP3 inflammasome in macrophages

    DOI: 10.1016/j.jff.2021.104364
    Sample: Cell culture medium
  252. Journal of Functional Foods (2021) IF: 4.451
    Effect of κ-carrageenan on glucolipid metabolism and gut microbiota in high-fat diet-fed mice

    DOI: 10.1016/j.jff.2021.104707
    Sample: serum
  253. Journal of Functional Foods (2022) IF: 4.451
    Antioxidative mechanisms and anticolitic potential of Desmodium styracifolium (Osb.) Merr. in DSS-induced colitic mice

    DOI: 10.1016/j.jff.2022.105077
    Sample: colonic tissue
  254. NEUROBIOLOGY OF AGING (2018) IF: 4.454
    CIP2A-promoted astrogliosis induces AD-like synaptic degeneration and cognitive deficits

    DOI: 10.1016/j.neurobiolaging.2018.11.023

    PMID: 30594047

    		 Sample: Tissue homogenate,Cell culture medium
  255. TOXICOLOGY AND APPLIED PHARMACOLOGY (2023) IF: 4.46
    Dihydrokaempferol attenuates CCl4-induced hepatic fibrosis by inhibiting PARP-1 to affect multiple downstream pathways and cytokines

    DOI: 10.1016/j.taap.2023.116438
    Sample: serum
  256. INFLAMMOPHARMACOLOGY (2021) IF: 4.473
    Terpene-rich fractions of Ficus mucoso (Welw) modulate lipopolysaccharide-induced inflammatory mediators and aberrant permeability of the inner mitochondrial membrane in murine animal model

    DOI: 10.1007/s10787-021-00876-x

    PMID: 34613566

    		 Sample: serum
  257. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020) IF: 4.486
    The stiffness‐controlled release of interleukin‐6 by cardiac fibroblasts is dependent on integrin α2β1

    DOI: 10.1111/jcmm.15974
    Sample: Serum
  258. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020) IF: 4.486
    Polysaccharides from Dicliptera chinensis ameliorate liver disturbance by regulating TLR‐4/NF‐κB and AMPK/Nrf2 signalling pathways

    DOI: 10.1111/jcmm.15286
    Sample: Serum,Tissue homogenate
  259. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020) IF: 4.486
    Defibrotide inhibits donor leucocyte‐endothelial interactions and protects against acute graft‐versus‐host disease

    DOI: 10.1111/jcmm.15434
    Sample: Plasma
  260. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2019) IF: 4.527
    Inflammatory kidney injury in trichloroethylene hypersensitivity syndrome mice: Possible role of C3a receptor in the accumulation of Th17 phenotype

    DOI: 10.1016/j.ecoenv.2019.109772

    PMID: 31614297

    		 Sample: Serum
  261. MEDIATORS OF INFLAMMATION (2023) IF: 4.529
    Integrative Analysis of Transcriptome and Metabolome to Illuminate the Protective Effects of Didymin against Acute Hepatic Injury

    DOI: 10.1155/2023/6051946
    Sample: Serum
  262. BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
    Study on the protective effect and mechanism of Dicliptera chinensis (L.) Juss (Acanthaceae) polysaccharide on immune liver injury induced by LPS

    DOI: 10.1016/j.biopha.2020.111159

    PMID: 33370627

    		 Sample: Tissue homogenate
  263. BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
    MG-132 attenuates cardiac deterioration of viral myocarditis via AMPK pathway

    DOI: 10.1016/j.biopha.2020.110091

    PMID: 32278272

    		 Sample: Plasma
  264. BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
    Marein ameliorates diabetic nephropathy by inhibiting renal sodium glucose transporter 2 and activating the AMPK signaling pathway in db/db mice and high glucose–treated HK-2 cells

    DOI: 10.1016/j.biopha.2020.110684
    Sample: serum
  265. BIOMEDICINE & PHARMACOTHERAPY (2020) IF: 4.545
    Dihydrotanshinone attenuates chemotherapy-induced intestinal mucositis and alters fecal microbiota in mice

    DOI: 10.1016/j.biopha.2020.110262
    Sample: serum
  266. Nutrients (2020) IF: 4.546
    Fermented Morinda citrifolia (Noni) Alleviates DNCB-Induced Atopic Dermatitis in NC/Nga Mice through Modulating Immune Balance and Skin Barrier Function

    DOI: 10.3390/nu12010249

    PMID: 31963703

    		 Sample: Serum,Cell culture supernatant
  267. Nutrients (2020) IF: 4.546
    Chinese Propolis Prevents Obesity and Metabolism Syndromes Induced by a High Fat Diet and Accompanied by an Altered Gut Microbiota Structure in Mice

    DOI: 10.3390/nu12040959

    PMID: 32235581

    		 Sample: Serum
  268. Nutrients (2020) IF: 4.546
    Bifidobacteria-Fermented Red Ginseng and Its Constituents Ginsenoside Rd and Protopanaxatriol Alleviate Anxiety/Depression in Mice by the Amelioration of Gut Dysbiosis

    DOI: 10.3390/nu12040901

    PMID: 32224881

    		 Sample: Tissue homogenate
  269. Frontiers in Physiology (2021) IF: 4.566
    Osthole Blocks HMGB1 Release From the Nucleus and Confers Protective Effects Against Renal Ischemia-Reperfusion Injury.

    DOI: 10.3389/fphys.2021.735425
    Sample: renal tissue
  270. MEDIATORS OF INFLAMMATION (2021) IF: 4.711
    The Protective Effect of Anthocyanins Extracted from Aronia Melanocarpa Berry in Renal Ischemia-Reperfusion Injury in Mice

    DOI: 10.1155/2021/7372893

    PMID: 33551679

    		 Sample: Serum
  271. MEDIATORS OF INFLAMMATION (2022) IF: 4.711
    Curcumin Targeting NF-κB/Ubiquitin-Proteasome-System Axis Ameliorates Muscle Atrophy in Triple-Negative Breast Cancer Cachexia Mice

    DOI: 10.1155/2022/2567150
    Sample: gastrocnemius tissue,4T1 cell-Xenograft
  272. Frontiers in Immunology (2019) IF: 4.716
    Intranasal MMI-0100 Attenuates Aβ1−42- and LPS-Induced Neuroinflammation and Memory Impairments via the MK2 Signaling Pathway

    DOI: 10.3389/fimmu.2019.02707
    Sample: Tissue homogenate
  273. JOURNAL OF PSYCHIATRIC RESEARCH (2021) IF: 4.791
    Lipopolysaccharide exacerbates chronic restraint stress-induced neurobehavioral deficits: Mechanisms by redox imbalance, ASK1-related apoptosis, autophagic dysregulation

    DOI: 10.1016/j.jpsychires.2021.10.021

    PMID: 34768069

    		 Sample: serum,brain
  274. JOURNAL OF PHARMACY AND PHARMACOLOGY (2023) IF: 4.81
    Inula japonica ameliorated the inflammation and oxidative stress in LPS-induced acute lung injury through the MAPK/NF-κB and Keap1/Nrf2 signalling pathways

    DOI: 10.1093/jpp/rgac084
    Sample: lung
  275. Oxidative Medicine and Cellular Longevity (2019) IF: 4.868
    Targeting IL-17A Improves the Dysmotility of the Small Intestine and Alleviates the Injury of the Interstitial Cells of Cajal during Sepsis

    DOI: 10.1155/2019/1475729

    PMID: 31531179

    		 Sample: Tissue homogenate
  276. Oxidative Medicine and Cellular Longevity (2019) IF: 4.868
    Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway

    DOI: 10.1155/2019/5813985
    Sample: blood
  277. Oxidative Medicine and Cellular Longevity (2019) IF: 4.868
    Maggot Extracts Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis via the Activation of Nrf2

    DOI: 10.1155/2019/4703253

    PMID: 31827675

    		 Sample: Serum
  278. Biomolecules (2021) IF: 4.879
    The Role of Indoleamine 2,3-Dioxygenase in Renal Tubular Epithelial Cells Senescence under Anoxia or Reoxygenation

    DOI: 10.3390/biom11101522

    PMID: 34680153

    		 Sample: RPTEC
  279. MOLECULES (2022) IF: 4.927
    Two Pairs of 7,7′-Cyclolignan Enantiomers with Anti-Inflammatory Activities from Perilla frutescens

    DOI: 10.3390/molecules27186102
    Sample: Raw 264.7 cell
  280. MOLECULES (2023) IF: 4.927
    Neuroprotective Effects of Savinin on LPS-Induced Neuroinflammation In Vivo via Regulating MAPK/NF-κB Pathway and NLRP3 Inflammasome Activation

    DOI: 10.3390/molecules28041575
    Sample: Serum
  281. MOLECULES (2022) IF: 4.927
    Monkfish (Lophius litulon) Peptides Ameliorate High-Fat-Diet-Induced Nephrotoxicity by Reducing Oxidative Stress and Inflammation via Regulation of Intestinal Flora

    DOI: 10.3390/molecules28010245
    Sample: renal tissue
  282. INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
    Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway

    DOI: 10.1016/j.intimp.2021.108238

    PMID: 34688152

    		 Sample: RGCs
  283. INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
    Protective effect of combination of anakinra and MCC950 against acute lung injury is achieved through suppression of the NF-κB-mediated-MAPK and NLRP3-caspase pathways

    DOI: 10.1016/j.intimp.2021.107506

    PMID: 34022766

    		 Sample: Tissue homogenate(lung),Bronchoalveolar Lavage Flu
  284. INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
    Oxymatrine inhibits neuroinflammation by Regulating M1/M2 polarization in N9 microglia through the TLR4/NF-κB pathway

    DOI: 10.1016/j.intimp.2021.108139
    Sample: N9 microglial cell
  285. INTERNATIONAL IMMUNOPHARMACOLOGY (2022) IF: 4.932
    Inhibition of P2Y6 receptor expression in Kupffer cells alleviates alcoholic steatohepatitis in mice

    DOI: 10.1016/j.intimp.2022.108909

    PMID: 35700583

    		 Sample: serum,RAW264.7 cell
  286. INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
    Hydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice

    DOI: 10.1016/j.intimp.2021.107583

    PMID: 33773206

    		 Sample: Tissue homogenate(hippocampal tissues)
  287. INTERNATIONAL IMMUNOPHARMACOLOGY (2022) IF: 4.932
    High-density lipoprotein reduces microglia activation and protects against experimental autoimmune encephalomyelitis in mice

    DOI: 10.1016/j.intimp.2022.108566

    PMID: 35101849

    		 Sample: plasma,BV2 microglial cell
  288. INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
    Empagliflozin, a sodium glucose cotransporter-2 inhibitor, ameliorates peritoneal fibrosis via suppressing TGF-β/Smad signaling

    DOI: 10.1016/j.intimp.2021.107374

    PMID: 33517222

    		 Sample: peritoneal dialysis solution,Cell culture supernat
  289. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 4.932
    COX-2-PGE2 signaling pathway contributes to hippocampal neuronal injury and cognitive impairment in PTZ-kindled epilepsy mice

    DOI: 10.1016/j.intimp.2020.106801
    Sample: Tissue homogenate
  290. INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
    Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway

    DOI: 10.1016/j.intimp.2021.108266

    PMID: 34678694

    		 Sample: BALF
  291. INTERNATIONAL IMMUNOPHARMACOLOGY (2022) IF: 4.932
    Atractyloside-A ameliorates spleen deficiency diarrhea by interfering with TLR4/MyD88/NF-κB signaling activation and regulating intestinal flora homeostasis

    DOI: 10.1016/j.intimp.2022.108679

    PMID: 35279514

    		 Sample: colon tissue
  292. INTERNATIONAL IMMUNOPHARMACOLOGY (2021) IF: 4.932
    Artesunate attenuates atherosclerosis by inhibiting macrophage M1-like polarization and improving metabolism

    DOI: 10.1016/j.intimp.2021.108413

    PMID: 34891003

    		 Sample: plasma
  293. INTERNATIONAL IMMUNOPHARMACOLOGY (2019) IF: 4.932
    Arsenic trioxide improves Treg and Th17 balance by modulating STAT3 in treatment-naïve rheumatoid arthritis patients

    DOI: 10.1016/j.intimp.2019.05.001
    Sample: serum
  294. PPAR Research (2019) IF: 4.964
    Arsenic Trioxide in Synergy with Vitamin D Rescues the Defective VDR-PPAR- Functional Module of Autophagy in Rheumatoid Arthritis

    DOI: 10.1155/2019/6403504
    Sample: serum
  295. FASEB JOURNAL (2020) IF: 4.966
    CaMK4‐dependent phosphorylation of Akt/mTOR underlies Th17 excessive activation in experimental autoimmune prostatitis

    DOI: 10.1096/fj.201902910RRR
    Sample: Cell culture supernatant,Tissue homogenate,serum
  296. Scientific Reports (2022) IF: 4.996
    Conditioned medium of mesenchymal stem cells pretreated with H2O2 promotes intestinal mucosal repair in acute experimental colitis

    DOI: 10.1038/s41598-022-24493-y
    Sample: colon tissue
  297. Contrast Media & Molecular Imaging (2022) IF: 3.009
    lncRNA SNHG12 Inhibition Based on Microsystem Cell Imaging Technology Protects the Endothelium from LPS-Induced Inflammation by Inhibiting the Expression of miR-140-3p Target Gene fndc5

    DOI: 10.1155/2022/1681864

    PMID: 36034208

    		 Sample: BALF,PMVEC
  298. Cardiovascular Therapeutics (2022) IF: 3.023
    L-Carnitine Alleviates the Myocardial Infarction and Left Ventricular Remodeling through Bax/Bcl-2 Signal Pathway

    DOI: 10.1155/2022/9615674

    PMID: 35692375

    		 Sample: plasma
  299. European Review for Medical and Pharmacological Sciences (2020) IF: 3.024
    MiR-181-5p protects mice from sepsis via repressing HMGB1 in an experimental model

    DOI: 10.26355/eurrev_202009_23063

    PMID: 33015817

    		 Sample: Serum
  300. NEUROCHEMICAL RESEARCH (2020) IF: 3.038
    Bexarotene Improve Depression-Like Behaviour in Mice by Protecting Against Neuro-inflammation and Synaptic Damage

    DOI: 10.1007/s11064-020-03012-3

    PMID: 32170675

    		 Sample: Tissue homogenate
  301. MOLECULES (2019) IF: 3.06
    MMI-0100 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice through Targeting MK2 Pathway

    DOI: 10.3390/molecules24152832
    Sample: colon
  302. MOLECULES (2019) IF: 3.06
    Design, Synthesis and Investigation of the Potential Anti-Inflammatory Activity of 7-O-Amide Hesperetin Derivatives

    DOI: 10.3390/molecules24203663

    PMID: 31614601

    		 Sample: Cell culture supernatant
  303. American Journal of Translational Research (2018) IF: 3.061
    Diosgenin glucoside protects against myocardial injury in diabetic mice by inhibiting RIP140 signaling

    PMID: 30662624

    		 Sample: serum,cardiac tissue
  304. MOLECULES (2018) IF: 3.098
    Nuciferine Inhibits Proinflammatory Cytokines via the PPARs in LPS-Induced RAW264.7 Cells

    DOI: 10.3390/molecules23102723
    Sample: Cell culture supernatant
  305. INTERNATIONAL IMMUNOPHARMACOLOGY (2018) IF: 3.118
    B-cell-specific mammalian target of rapamycin complex 1 activation results in severe osteoarthritis in mice

    DOI: 10.1016/j.intimp.2018.09.038
    Sample: serum
  306. Journal of Pain Research (2022) IF: 3.133
    Anti-Nociceptive and Anti-Inflammatory Activities of the Ethyl Acetate Extract of Belamcanda chinensis (L.) Redouté in Raw 264.7 Cells in vitro and Mouse Model in vivo

    DOI: 10.2147/JPR.S353357

    PMID: 35502404

    		 Sample: RAW264.7 cell
  307. EUROPEAN JOURNAL OF PHARMACOLOGY (2019) IF: 3.17
    Pancreastatin inhibitor PSTi8 attenuates hyperinsulinemia induced obesity and inflammation mediated insulin resistance via MAPK/NOX3-JNK pathway

    DOI: 10.1016/j.ejphar.2019.172723

    PMID: 31586632

    		 Sample: Plasma
  308. EUROPEAN JOURNAL OF PHARMACOLOGY (2019) IF: 3.17
    Circular RNA expression profile of liver tissues in an EtOH-induced mouse model of alcoholic hepatitis

    DOI: 10.1016/j.ejphar.2019.172642

    PMID: 31493407

    		 Sample: Serum,Tissue homogenate
  309. Journal of Functional Foods (2019) IF: 3.197
    Anti-fatigue activity of purified anthocyanins prepared from purple passion fruit (P. edulis Sim) epicarp in mice

    DOI: 10.1016/j.jff.2019.103725
    Sample: Tissue homogenate
  310. INFLAMMATION (2020) IF: 3.212
    miR-128-3p Inhibits NRP1 Expression and Promotes Inflammatory Response to Acute Kidney Injury in Sepsis

    DOI: 10.1007/s10753-020-01251-8
    Sample: TCMK-1 cell
  311. INFLAMMATION (2020) IF: 3.212
    Casticin Attenuates Osteoarthritis-Related Cartilage Degeneration by Inhibiting the ROS-Mediated NF-κB Signaling Pathway in vitro and in vivo

    DOI: 10.1007/s10753-019-01167-y
    Sample: serum,ADTC5 cell
  312. ACTA PHARMACOLOGICA SINICA (2017) IF: 3.223
    Osthole prevents acetaminophen-induced liver injury in mice

    DOI: 10.1038/aps.2017.129
    Sample: Tissue homogenate
  313. Cardiovascular Toxicology (2021) IF: 3.239
    Diet-Derived Advanced Glycation End Products (dAGEs) Induce Proinflammatory Cytokine Expression in Cardiac and Renal Tissues of Experimental Mice: Protective Effect of Curcumin

    DOI: 10.1007/s12012-021-09697-4

    PMID: 34655413

    		 Sample: serum
  314. Food & Function (2019) IF: 3.241
    Propacin, a coumarinolignoid isolated from durian, inhibits the lipopolysaccharide-induced inflammatory response in macrophages through the MAPK and NF-κB pathways

    DOI: 10.1039/C9FO02202C

    PMID: 31859327

    		 Sample: Cell culture supernatant
  315. IUBMB LIFE (2020) IF: 3.244
    Blockade of high mobility group box 1 involved in the protective of curcumin on myocardial injury in diabetes in vivo and in vitro

    DOI: 10.1002/iub.2226

    PMID: 31909882

    		 Sample: Serum
  316. EUROPEAN JOURNAL OF PHARMACOLOGY (2020) IF: 3.263
    Glucagon-like peptide-1 cleavage product GLP-1(9–36) reduces neuroinflammation from stroke via the activation of insulin-like growth factor 1 receptor in astrocytes

    DOI: 10.1016/j.ejphar.2020.173581
    Sample: Cell culture supernatant
  317. MOLECULES (2020) IF: 3.267
    Anti-Inflammatory Effect of Simonsinol on Lipopolysaccharide Stimulated RAW264.7 Cells through Inactivation of NF-κB Signaling Pathway

    DOI: 10.3390/molecules25163573

    PMID: 32781605

    		 Sample: Cell culture supernatant
  318. MOLECULES (2020) IF: 3.267
    A Herbal Mixture from Propolis, Pomegranate, and Grape Pomace Endowed with Anti-Inflammatory Activity in an In Vivo Rheumatoid Arthritis Model

    DOI: 10.3390/molecules25092255
    Sample: serum
  319. Bioengineered (2021) IF: 3.269
    Synergetic protective effect of berberine and ginsenoside Rb1 against tumor necrosis factor alpha−induced inflammation in adipocytes

    DOI: 10.1080/21655979.2021.1996508
    Sample: 3T3-L1 preadipocyte
  320. Bioengineered (2022) IF: 3.269
    Shikonin combined with methotrexate regulate macrophage polarization to treat psoriasis

    DOI: 10.1080/21655979.2022.2062090

    PMID: 35485255

    		 Sample: RAW264.7 cell
  321. Bioengineered (2022) IF: 3.269
    Guizhi Fuling pill attenuates liver fibrosis in vitro and in vivo via inhibiting TGF-β1/Smad2/3 and activating IFN-γ/Smad7 signaling pathways

    DOI: 10.1080/21655979.2022.2054224

    PMID: 35387552

    		 Sample: liver tissue
  322. Bioengineered (2021) IF: 3.269
    Cabergoline possesses a beneficial effect on blood-brain barrier (BBB) integrity against lipopolysaccharide (LPS)

    DOI: 10.1080/21655979.2021.1987066

    PMID: 34592907

    		 Sample: brain tissue
  323. NEUROSCIENCE (2017) IF: 3.277
    Blocking the CD38/cADPR pathway plays a double-edged role in LPS stimulated microglia

    DOI: 10.1016/j.neuroscience.2017.08.010
    Sample: Cell culture supernatant
  324. FISH & SHELLFISH IMMUNOLOGY (2019) IF: 3.298
    Anti-inflammatory effect of a novel synthetic compound 1-((4-fluorophenyl)thio)isoquinoline in RAW264.7 macrophages and a zebrafish model

    DOI: 10.1016/j.fsi.2019.01.030
    Sample: Cell culture supernatant
  325. CELL CYCLE (2018) IF: 3.304
    MicroRNA-27a alleviates LPS-induced acute lung injury in mice via inhibiting inflammation and apoptosis through modulating TLR4/MyD88/NF-κB pathway

    DOI: 10.1080/15384101.2018.1509635
    Sample: bronchoalveolar lavage fluid (BALF),RAW 264.7 cell
  326. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy (2019) IF: 3.319
    2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione isolated from Averrhoa carambola L. root ameliorates diabetic nephropathy by inhibiting the TLR4/MyD88/NF-κB pathway

    DOI: 10.2147/DMSO.S209436
    Sample: kidney
  327. INTERNATIONAL IMMUNOPHARMACOLOGY (2019) IF: 3.361
    Regulation of CD39 expression in ATP-P2Y2R-mediated alcoholic liver steatosis and inflammation

    DOI: 10.1016/j.intimp.2019.105915

    PMID: 31639617

    		 Sample: Serum,Cell culture supernatant
  328. CELLULAR & MOLECULAR BIOLOGY LETTERS (2019) IF: 3.367
    Tetrahydroxy stilbene glucoside alleviates palmitic acid-induced inflammation and apoptosis in cardiomyocytes by regulating miR-129-3p/Smad3 signaling

    DOI: 10.1186/s11658-018-0125-x

    PMID: 30820195

    		 Sample: Cell culture supernatant
  329. CELLULAR & MOLECULAR BIOLOGY LETTERS (2019) IF: 3.367
    Honokiol alleviates sepsis-induced acute kidney injury in mice by targeting the miR-218-5p/heme oxygenase-1 signaling pathway

    DOI: 10.1186/s11658-019-0142-4

    PMID: 30833971

    		 Sample: Serum
  330. American Journal of Translational Research (2020) IF: 3.375
    Overexpression of lncRNA Gm43050 alleviates apoptosis and inflammation response induced by sevoflurane treatment by regulating miR-640/ZFP91

    PMID: 32913509

    		 Sample: primary hippocampal neurons
  331. JOURNAL OF DRUG TARGETING (2020) IF: 3.38
    Development, optimisation and evaluation of chitosan nanoparticles of alendronate against Alzheimer’s disease in intracerebroventricular streptozotocin model for brain delivery

    DOI: 10.1080/1061186X.2020.1817041
    Sample: Tissue homogenate
  332. PPAR Research (2018) IF: 3.386
    Portulaca Extract Attenuates Development of Dextran Sulfate Sodium Induced Colitis in Mice through Activation of PPARγ

    DOI: 10.1155/2018/6079101
    Sample: serum
  333. Brain Sciences (2022) IF: 3.394
    Suppressive Effects of Gelsemine on Anxiety-like Behaviors Induced by Chronic Unpredictable Mild Stress in Mice

    DOI: 10.3390/brainsci12020191

    PMID: 35203954

    		 Sample: brain tissue
  334. Brain and Behavior (2022) IF: 3.405
    MiR-340-5p alleviates neuroinflammation and neuronal injury via suppressing STING in subarachnoid hemorrhage

    DOI: 10.1002/brb3.2687

    PMID: 35957622

    		 Sample: brain tissue,microglia
  335. CHEMICO-BIOLOGICAL INTERACTIONS (2019) IF: 3.407
    Pregnane X receptor activation by its natural ligand Ginkgolide-A improves tight junction proteins expression and attenuates bacterial translocation in cirrhosis

    DOI: 10.1016/j.cbi.2019.108891

    PMID: 31697926

    		 Sample: Plasma,Tissue homogenate
  336. Biomed Research International (2021) IF: 3.411
    VX765, a Specific Caspase-1 Inhibitor, Alleviates Lung Ischemia Reperfusion Injury by Suppressing Endothelial Pyroptosis and Barrier Dysfunction

    DOI: 10.1155/2021/4525988

    PMID: 34977239

    		 Sample: lung tissue,serum,PMVEC
  337. Biomed Research International (2021) IF: 3.411
    Protective Effect of Luteolin on D-Galactosamine (D-Gal)/Lipopolysaccharide (LPS) Induced Hepatic Injury by in Mice

    DOI: 10.1155/2021/2252705

    PMID: 34368345

    		 Sample: serum,liver
  338. PSYCHOPHARMACOLOGY (2019) IF: 3.424
    The protective effect of Geniposide on diabetic cognitive impairment through BTK/TLR4/NF-κB pathway

    DOI: 10.1007/s00213-019-05379-w

    PMID: 31811349

    		 Sample: Serum
  339. JOURNAL OF CELLULAR BIOCHEMISTRY (2019) IF: 3.448
    Attractylone attenuates sepsis‐associated encephalopathy and cognitive dysfunction by inhibiting microglial activation and neuroinflammation

    DOI: 10.1002/jcb.27983
    Sample: Cell culture supernatant,Tissue homogenate
  340. BIOMEDICINE & PHARMACOTHERAPY (2018) IF: 3.457
    The protective effect of formononetin on cognitive impairment in streptozotocin (STZ)-induced diabetic mice

    DOI: 10.1016/j.biopha.2018.07.063
    Sample: Serum,Tissue homogenate
  341. Biomolecules & Therapeutics (2020) IF: 3.47
    Antineuroinflammatory Effects of 7,3’,4’-Trihydroxyisoflavone in Lipopolysaccharide-Stimulated BV2 Microglial Cells through MAPK and NF-κB Signaling Suppression

    DOI: 10.4062/biomolther.2020.093
    Sample: Cell culture supernatant
  342. DIGESTIVE DISEASES AND SCIENCES (2022) IF: 3.487
    Mesenchymal Stem Cells Promote Intestinal Mucosal Repair by Positively Regulating the Nrf2/Keap1/ARE Signaling Pathway in Acute Experimental Colitis

    DOI: 10.1007/s10620-022-07722-2
    Sample: colon tissue
  343. JOURNAL OF ORTHOPAEDIC RESEARCH (2020) IF: 3.494
    Curcumin prevents osteocyte apoptosis by inhibiting M1‐type macrophage polarization in mice model of glucocorticoid‐associated osteonecrosis of the femoral head

    DOI: 10.1002/jor.24619
    Sample: peripheral blood
  344. TOXICOLOGY IN VITRO (2021) IF: 3.5
    (3α)-3-(tiglinoyloxy)-ent-kaur-16-en-19-oic acid, isolated from Wedelia trilobata L., exerts an anti-inflammatory effect via the modulation of NF-κB, MAPK and mTOR pathway and autophagy in LPS-stimulated macrophages

    DOI: 10.1016/j.tiv.2021.105139

    PMID: 33705895

    		 Sample: Cell culture supernatant
  345. ACS Omega (2022) IF: 3.512
    Macrophage Distribution Affected by Virus-Encoded Granulocyte Macrophage Colony Stimulating Factor Combined with Lactate Oxidase

    DOI: 10.1021/acsomega.2c03213

    PMID: 35847295

    		 Sample: RAW264.7 cell
  346. PHOTOCHEMISTRY AND PHOTOBIOLOGY (2023) IF: 3.521
    Dendrobium Nobile Lindl Polysaccharides Attenuate UVB-Induced Photodamage by Regulating Oxidative Stress, Inflammation and Mmps Expression in Mice Model

    DOI: 10.1111/php.13780
    Sample: skin
  347. Toxicology Research (2021) IF: 3.524
    The modulatory impacts of Glycyrrhiza glabra extract against methotrexate-induced testicular dysfunction and oxidative stress

    DOI: 10.1093/toxres/tfab049
    Sample: serum
  348. TOXICOLOGY (2019) IF: 3.547
    4-Methylcoumarin-[5,6–g]-hesperetin attenuates inflammatory responses in alcoholic hepatitis through PPAR-γ activation

    DOI: 10.1016/j.tox.2019.04.004

    PMID: 30951781

    		 Sample: Serum,Cell culture supernatant
  349. MOLECULAR AND CELLULAR ENDOCRINOLOGY (2018) IF: 3.563
    Curcumin restrains hepatic glucose production by blocking cAMP/PKA signaling and reducing acetyl CoA accumulation in high-fat diet (HFD)-fed mice

    DOI: 10.1016/j.mce.2018.02.018
    Sample: liver
  350. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2018) IF: 3.569
    Upregulated galectin-3 is not a critical disease mediator of cardiomyopathy induced by β2-adrenoceptor overexpression

    DOI: 10.1152/ajpheart.00337.2017
    Sample: left ventricle (LV) tissues
  351. TOXICOLOGY LETTERS (2020) IF: 3.569
    Methamphetamine induced neuroinflammation in mouse brain and microglial cell line BV2: Roles of the TLR4/TRIF/Peli1 signaling axis

    DOI: 10.1016/j.toxlet.2020.07.028

    PMID: 32768653

    		 Sample: Cell culture supernatant,Tissue homogenate
  352. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022) IF: 3.575
    Sulforaphane protects myocardium from ischemia-reperfusion injury by regulating CaMKIIN2 and CaMKIIδ

    DOI: 10.1016/j.bbrc.2022.03.015

    PMID: 35316762

    		 Sample: H9c2 cell
  353. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2022) IF: 3.575
    Loss of serine/threonine protein kinase 25 in retinal ganglion cells ameliorates high glucose-elicited damage through regulation of the AKT-GSK-3β/Nrf2 pathway

    DOI: 10.1016/j.bbrc.2022.02.044

    PMID: 35217361

    		 Sample: retina ganglion cell
  354. NEUROSCIENCE (2022) IF: 3.59
    Pharmacological Postconditioning by Protocatechuic Acid Attenuates Brain Injury in Ischemia–Reperfusion (I/R) Mice Model: Implications of Nuclear Factor Erythroid-2-Related Factor Pathway

    DOI: 10.1016/j.neuroscience.2022.03.016
    Sample: brain
  355. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2020) IF: 3.606
    Protective roles and mechanisms of rosmarinic acid in cyclophosphamide‐induced premature ovarian failure

    DOI: 10.1002/jbt.22591
    Sample: Serum
  356. TOXICOLOGY AND APPLIED PHARMACOLOGY (2018) IF: 3.616
    SIRT1 activation by butein attenuates sepsis-induced brain injury in mice subjected to cecal ligation and puncture via alleviating inflammatory and oxidative stress

    DOI: 10.1016/j.taap.2018.10.013

    PMID: 30336174

    		 Sample: Serum,Tissue homogenate
  357. Frontiers in Endocrinology (2020) IF: 3.644
    The Protective Effects of Melatonin Against LPS-Induced Septic Myocardial Injury: A Potential Role of AMPK-Mediated Autophagy

    DOI: 10.3389/fendo.2020.00162

    PMID: 32373063

    		 Sample: Serum
  358. LIFE SCIENCES (2020) IF: 3.647
    Pretreatment of exosomes derived from hUCMSCs with TNF-α ameliorates acute liver failure by inhibiting the activation of NLRP3 in macrophage

    DOI: 10.1016/j.lfs.2020.117401

    PMID: 32035931

    		 Sample: Whole Blood,Tissue homogenate
  359. LIFE SCIENCES (2020) IF: 3.647
    Effects of taraxasterol against ethanol and high-fat diet-induced liver injury by regulating TLR4/MyD88/NF-κB and Nrf2/HO-1 signaling pathways

    DOI: 10.1016/j.lfs.2020.118546

    PMID: 33035580

    		 Sample: Serum
  360. Food & Nutrition Research (2020) IF: 3.647
    Camellia cake extracts reduce burn injury through suppressing inflammatory responses and enhancing collagen synthesis

    DOI: 10.29219/fnr.v64.3782

    PMID: 32425739

    		 Sample: Tissue homogenate
  361. JOURNAL OF FOOD BIOCHEMISTRY (2022) IF: 3.654
    Exploring the potential of Lacticaseibacillus paracasei M11 on antidiabetic, anti-inflammatory, and ACE inhibitory effects of fermented dromedary camel milk (Camelus dromedaries) and the release of antidiabetic and anti-hypertensive peptides

    DOI: 10.1111/jfbc.14449

    PMID: 36206543

    		 Sample: RAW 264.7 cells
  362. METABOLIC BRAIN DISEASE (2022) IF: 3.655
    Genistein suppresses microglial activation and inhibits apoptosis in different brain regions of hypoxia-exposed mice model of amnesia

    DOI: 10.1007/s11011-022-01039-9

    PMID: 35895244

    		 Sample: Hippocampus tissue
  363. METABOLIC BRAIN DISEASE (2022) IF: 3.655
    CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen–glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway

    DOI: 10.1007/s11011-022-01043-z
    Sample: HT22 neurons
  364. GENE (2019) IF: 3.688
    The inhibition of microRNA-203 on ischemic reperfusion injury after total knee arthroplasty via suppressing MYD88-mdiated toll-like receptor signaling pathway

    DOI: 10.1016/j.gene.2019.02.030

    PMID: 30772517

    		 Sample: Tissue homogenate
  365. Biomedical Materials (2021) IF: 3.715
    The osteoimmunomodulatory effect of nanostructured TiF x /TiO x coating on osteogenesis induction

    DOI: 10.1088/1748-605X/ac0863
    Sample: RAW264.7 cells
  366. BRAIN RESEARCH BULLETIN (2023) IF: 3.715
    IGF2 inhibits hippocampal over-activated microglia and alleviates depression-like behavior in LPS- treated male mice

    DOI: 10.1016/j.brainresbull.2023.01.001
    Sample: Serum
  367. BIOLOGICAL TRACE ELEMENT RESEARCH (2021) IF: 3.738
    Sodium P-aminosalicylic Acid Attenuates Manganese-Induced Neuroinflammation in BV2 Microglia by Modulating NF-κB Pathway

    DOI: 10.1007/s12011-021-02581-w

    PMID: 33447908

    		 Sample: Cell culture supernatant(BV2 Cells)
  368. BIOLOGICAL TRACE ELEMENT RESEARCH (2021) IF: 3.738
    Borate Ameliorates Sodium Nitrite-Induced Oxidative Stress Through Regulation of Oxidant/Antioxidant Status: Involvement of the Nrf2/HO-1 and NF-κB Pathways

    DOI: 10.1007/s12011-021-02613-5

    PMID: 33559025

    		 Sample: Serum
  369. BIOMEDICINE & PHARMACOTHERAPY (2019) IF: 3.743
    Inhibition of the mitochondrial complex-1 protects against carbon tetrachloride-induced acute liver injury

    DOI: 10.1016/j.biopha.2019.108948
    Sample: liver
  370. BIOMEDICINE & PHARMACOTHERAPY (2019) IF: 3.743
    Combination of tanshinone IIA and astragaloside IV attenuate atherosclerotic plaque vulnerability in ApoE(-/-) mice by activating PI3K/AKT signaling and suppressing TRL4/NF-κB signaling

    DOI: 10.1016/j.biopha.2019.109729
    Sample: plasma,RAW264.7 cell
  371. Marine Drugs (2019) IF: 3.772
    Pepsin-Soluble Collagen from the Skin of Lophius litulo: A Preliminary Study Evaluating Physicochemical, Antioxidant, and Wound Healing Properties

    DOI: 10.3390/md17120708
    Sample: serum
  372. Heliyon (2022) IF: 3.776
    A sesquiterpene isolated from the stems and leaves of Dioscorea opposita thunb. Transforms the composition of immune cells through ERβ in a mouse model of LPS-induced lung injury

    DOI: 10.1016/j.heliyon.2022.e10500
    Sample: Serum,lung tissue,BEAS-2B cell
  373. JOURNAL OF NATURAL PRODUCTS (2020) IF: 3.782
    3α-Angeloyloxy-ent-kaur-16-en-19-oic Acid Isolated from Wedelia trilobata L. Alleviates Xylene-Induced Mouse Ear Edema and Inhibits NF-κB and MAPK Pathway in LPS-Stimulated Macrophages

    DOI: 10.1021/acs.jnatprod.0c00990
    Sample: Cell culture medium,Tissue Slice
  374. Frontiers in Pharmacology (2019) IF: 3.845
    Suhuang Antitussive Capsules-Ameliorative Effects on LPS-Induced Sputum Obstruction in Mice Through Promoting HGF Secretion

    DOI: 10.3389/fphar.2019.01422
    Sample: Serum,Tissue homogenate
  375. Frontiers in Medicine (2020) IF: 3.9
    Adiponectin Inhibits NLRP3 Inflammasome Activation in Nonalcoholic Steatohepatitis via AMPK-JNK/ErK1/2-NFκB/ROS Signaling Pathways

    DOI: 10.3389/fmed.2020.546445

    PMID: 33251225

    		 Sample: Tissue homogenate(liver tissue)
  376. JOURNAL OF CELLULAR PHYSIOLOGY (2018) IF: 3.923
    Blocking PI3K/AKT signaling inhibits bone sclerosis in subchondral bone and attenuates post‐traumatic osteoarthritis

    DOI: 10.1002/jcp.26460
    Sample: serum,preosteoblasts
  377. RESPIRATORY RESEARCH (2020) IF: 3.924
    Thymosin β10 promotes tumor-associated macrophages M2 conversion and proliferation via the PI3K/Akt pathway in lung adenocarcinoma

    DOI: 10.1186/s12931-020-01587-7
    Sample: RAW264.7 cell
  378. BIOORGANIC CHEMISTRY (2018) IF: 3.929
    Assessment of novel azaanthraquinone derivatives as potent multi-target inhibitors of inflammation and amyloid-β aggregation in Alzheimer’s disease

    DOI: 10.1016/j.bioorg.2018.10.073
    Sample: Cell culture medium
  379. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
    Saikosaponin-d attenuated lipopolysaccharide-induced depressive-like behaviors via inhibiting microglia activation and neuroinflammation

    DOI: 10.1016/j.intimp.2019.106181

    PMID: 31926446

    		 Sample: Cell sample,Tissue homogenate
  380. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
    NLRP12 negatively regulates EtOH-induced liver macrophage activation via NF-κB pathway and mediates hepatocyte apoptosis in alcoholic liver injury

    DOI: 10.1016/j.intimp.2020.106968

    PMID: 33182058

    		 Sample: serum,RAW 264.7 cell
  381. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
    Molecular hydrogen attenuates sepsis-induced neuroinflammation through regulation of microglia polarization through an mTOR-autophagy-dependent pathway

    DOI: 10.1016/j.intimp.2020.106287

    PMID: 32058932

    		 Sample: Tissue homogenate
  382. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
    miR-129-5p alleviates LPS-induced acute kidney injury via targeting HMGB1/TLRs/NF-kappaB pathway

    DOI: 10.1016/j.intimp.2020.107016

    PMID: 33039954

    		 Sample: Serum
  383. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
    Inhibition of HMGB1 involved in the protective of salidroside on liver injury in diabetes mice

    DOI: 10.1016/j.intimp.2020.106987

    PMID: 33217691

    		 Sample: Cell culture supernatant,Serum,Tissue homogenate
  384. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
    Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice

    DOI: 10.1016/j.intimp.2020.107003

    PMID: 33182043

    		 Sample: Tissue homogenate
  385. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
    Betulin alleviates on myocardial inflammation in diabetes mice via regulating Siti1/NLRP3/NF-κB pathway

    DOI: 10.1016/j.intimp.2020.106653
    Sample: serum,heart
  386. INTERNATIONAL IMMUNOPHARMACOLOGY (2020) IF: 3.943
    10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells

    DOI: 10.1016/j.intimp.2020.106501
    Sample: Cell culture supernatant
  387. CARDIOVASCULAR DRUGS AND THERAPY (2022) IF: 3.947
    Sulfated Galactofucan from Sargassum Thunbergii Attenuates Atherosclerosis by Suppressing Inflammation Via the TLR4/MyD88/NF-κB Signaling Pathway

    DOI: 10.1007/s10557-022-07383-3

    PMID: 36194354

    		 Sample: serum,RAW264.7 cells
  388. NEUROCHEMICAL RESEARCH (2021) IF: 3.996
    Platinum nanoparticles Protect Against Lipopolysaccharide-Induced Inflammation in Microglial BV-2 Cells via Decreased Oxidative Damage and Increased Phagocytosis

    DOI: 10.1007/s11064-021-03434-7

    PMID: 34432181

    		 Sample: BV-2 cell
  389. Scientific Reports (2020) IF: 3.998
    Latexin deficiency in mice up-regulates inflammation and aggravates colitis through HECTD1/Rps3/NF-κB pathway

    DOI: 10.1038/s41598-020-66789-x

    PMID: 32555320

    		 Sample: Serum
  390. POULTRY SCIENCE (2019) IF: 2.027
    Anti-inflammatory effect of preserved egg with simulated gastrointestinal digestion on LPS-stimulated RAW264.7 cells

    DOI: 10.3382/ps/pez243

    PMID: 31041437

    		 Sample: Cell culture supernatant
  391. MEDICINE (2018) IF: 2.028
    Effect of gap junctions on RAW264.7 macrophages infected with H37Rv

    DOI: 10.1097/MD.0000000000012125
    Sample: Cell culture supernatant
  392. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2019) IF: 2.041
    Role of Brd4 in the production of inflammatory cytokines in mouse macrophages treated with titanium particles

    DOI: 10.1139/cjpp-2019-0142

    PMID: 31330113

    		 Sample: Cell culture supernatant
  393. Brain and Behavior (2020) IF: 2.091
    MicroRNA‐345‐5p regulates depression by targeting suppressor of cytokine signaling 1

    DOI: 10.1002/brb3.1653
    Sample: Cell culture supernatant
  394. Molecular Medicine Reports (2020) IF: 2.1
    Osthole inhibits proliferation of kainic acid‑activated BV‑2 cells by modulating the Notch signaling pathway

    DOI: 10.3892/mmr.2020.11455

    PMID: 33000274

    		 Sample: Cell culture supernatant
  395. Molecular Medicine Reports (2020) IF: 2.1
    Coenzyme Q10 alleviates sevoflurane‑induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons

    DOI: 10.3892/mmr.2020.11131
    Sample: Tissue homogenate
  396. Current Medical Science (2019) IF: 2.135
    Berberine Attenuates Cigarette Smoke Extract-induced Airway Inflammation in Mice: Involvement of TGF-β1/Smads Signaling Pathway

    DOI: 10.1007/s11596-019-2101-8

    PMID: 31612392

    		 Sample: Bronchoalveolar Lavage Fluid
  397. STEROIDS (2019) IF: 2.136
    Synthesis and evaluation of novel D-ring substituted steroidal pyrazolines as potential anti-inflammatory agents

    DOI: 10.1016/j.steroids.2019.03.012

    PMID: 30951758

    		 Sample: Cell culture supernatant
  398. International Journal of Peptide Research and Therapeutics (2022) IF: 2.191
    Atrial Natriuretic Peptide (ANP) Suppress λ-Carrageenan-Induced Acute Paw Edema by Modulating Pro-inflammatory Genes in Swiss Albino Mice

    DOI: 10.1007/s10989-022-10444-8
    Sample: paw tissue
  399. JOURNAL OF NEUROSCIENCE METHODS (2020) IF: 2.214
    Frequent exposure to varied home cage sizes alters pain sensitivity and some key inflammation-related biomarkers

    DOI: 10.1016/j.jneumeth.2020.108890

    PMID: 32768413

    		 Sample: Tissue homogenate
  400. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015) IF: 2.297
    Ghrelin ameliorates intestinal barrier dysfunction in experimental colitis by inhibiting the activation of nuclear factor-kappa B

    DOI: 10.1016/j.bbrc.2015.01.083
    Sample: Tissue homogenate
  401. HISTOLOGY AND HISTOPATHOLOGY (2021) IF: 2.303
    Death-associated protein kinase 1 correlates with podocyte apoptosis and renal damage and can be mediated by miR-361.

    DOI: 10.14670/hh-18-358
    Sample: renal podocytes
  402. REPRODUCTION FERTILITY AND DEVELOPMENT (2019) IF: 2.311
    Notch signalling regulates steroidogenesis in mouse ovarian granulosa cells

    DOI: 10.1071/RD18281

    PMID: 30827331

    		 Sample: Cell culture medium
  403. BMC Anesthesiology (2022) IF: 2.376
    Aerobic exercise alleviates ventilator-induced lung injury by inhibiting NLRP3 inflammasome activation

    DOI: 10.1186/s12871-022-01874-4
    Sample: Bronchoalveolar lavage fluid (BALF)
  404. PARASITOLOGY RESEARCH (2022) IF: 2.383
    Plasmodium knowlesi Duffy binding protein alpha region II (PkDBPαII) in clinical isolates from Peninsular Malaysia and Malaysian Borneo exhibit different immune responses in animal models

    DOI: 10.1007/s00436-022-07665-7

    PMID: 36152079

    		 Sample: Spleen cell
  405. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2019) IF: 2.422
    Effect and mechanism of citral against methicillin‐resistant Staphylococcus aureus in vivo

    DOI: 10.1002/jsfa.9677
    Sample: Serum
  406. Experimental and Therapeutic Medicine (2022) IF: 2.447
    LincRNA‑EPS increases TGF‑β expression to inhibit the Wnt/β‑catenin pathway, VSMC osteoblastic differentiation and vascular calcification in diabetic mice

    DOI: 10.3892/etm.2022.11352
    Sample: serum
  407. Experimental and Therapeutic Medicine (2020) IF: 2.447
    Clostridium butyricum protects intestinal barrier function via upregulation of tight junction proteins and activation of the Akt/mTOR signaling pathway in a mouse model of dextran sodium sulfate‑induced colitis

    DOI: 10.3892/etm.2020.9138
    Sample: Serum
  408. NEUROLOGICAL RESEARCH (2020) IF: 2.451
    The intervention mechanism of emodin on TLR3 pathway in the process of central nervous system injury caused by herpes virus infection

    DOI: 10.1080/01616412.2020.1853989

    PMID: 33274693

    		 Sample: Tissue homogenate
  409. TISSUE & CELL (2022) IF: 2.466
    Upregulation of BRD7 protects podocytes against high glucose-induced apoptosis by enhancing Nrf2 in a GSK-3β-dependent manner

    DOI: 10.1016/j.tice.2022.101813

    PMID: 35550209

    		 Sample: MPC-5 cell
  410. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2020) IF: 2.477
    Isolation, characterization and anti-inflammatory mechanism of probiotics in lipopolysaccharide-stimulated RAW 264.7 macrophages

    DOI: 10.1007/s11274-020-02852-z
    Sample: RAW 264.7 cell
  411. BIOSCIENCE REPORTS (2019) IF: 2.535
    Association of IL-6, IL-8, MMP-13 gene polymorphisms with knee osteoarthritis susceptibility in the Chinese Han population

    DOI: 10.1042/BSR20181346

    PMID: 30635366

    		 Sample: Tissue homogenate
  412. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018) IF: 2.559
    Eosinophils attenuate arthritis by inducing M2 macrophage polarization via inhibiting the IκB/P38 MAPK signaling pathway

    DOI: 10.1016/j.bbrc.2018.12.010
    Sample: Tissue homogenate,Cell culture supernatant
  413. MICROBIAL PATHOGENESIS (2019) IF: 2.581
    Metabolites of stable fly reduce diarrhea in mice by modulating the immune system, antioxidants, and composition of gut microbiota

    DOI: 10.1016/j.micpath.2019.103557
    Sample: serum,small intestinal tissues
  414. Biomed Research International (2018) IF: 2.583
    Upregulated TSG-6 Expression in ADSCs Inhibits the BV2 Microglia-Mediated Inflammatory Response

    DOI: 10.1155/2018/7239181
    Sample: BV2 cells
  415. JOURNAL OF MOLECULAR HISTOLOGY (2021) IF: 2.611
    MiRNA-182-5p aggravates experimental ulcerative colitis via sponging Claudin-2

    DOI: 10.1007/s10735-021-10021-1

    PMID: 34623552

    		 Sample: colonic tissue
  416. Evidence-based Complementary and Alternative Medicine (2022) IF: 2.63
    Camelina sativa Oil Treatment Alleviates Castor Oil-Induced Diarrhea in ICR Mice by Regulating Intestinal Flora Composition

    DOI: 10.1155/2022/5394514

    PMID: 35178105

    		 Sample: plasma
  417. ARCHIVES OF ORAL BIOLOGY (2023) IF: 2.64
    IL-37 alleviates alveolar bone resorption and inflammatory response through the NF-κB/NLRP3 signaling pathway in male mice with periodontitis

    DOI: 10.1016/j.archoralbio.2023.105629
    Sample: periodontal tissue
  418. Evidence-based Complementary and Alternative Medicine (2022) IF: 2.65
    Febuxostat Alleviates Allergic Rhinitis by Inhibiting Inflammation and Monocyte Adhesion in Human Nasal Epithelial Cells via Regulating KLF6.

    DOI: 10.1155/2022/9092311
    Sample: nasal mucosa tissue
  419. Evidence-based Complementary and Alternative Medicine (2022) IF: 2.65
    Exploring the Muscle Metabolomics in the Mouse Model of Sepsis-Induced Acquired Weakness

    DOI: 10.1155/2022/6908488

    PMID: 36016684

    		 Sample: serum
  420. Evidence-based Complementary and Alternative Medicine (2022) IF: 2.65
    Anti-inflammatory Mechanism of Action of Benzoylmesaconine in Lipopolysaccharide-Stimulated RAW264.7 Cells

    DOI: 10.1155/2022/7008907

    PMID: 35873638

    		 Sample: RAW264.7 cell
  421. STEROIDS (2021) IF: 2.668
    Synthesis and anti-inflammatory activity of novel steroidal chalcones with 3β-pregnenolone ester derivatives in RAW 264.7 cells in vitro

    DOI: 10.1016/j.steroids.2021.108830

    PMID: 33836205

    		 Sample: Cell culture supernatant
  422. Innate Immunity (2021) IF: 2.68
    Chrysosplenol D protects mice against LPS-induced acute lung injury by inhibiting oxidative stress, inflammation, and apoptosis via TLR4-MAPKs/NF-κB signaling pathways:

    DOI: 10.1177/17534259211051069
    Sample: Bronchoalveolar Lavage Fluid
  423. Iranian Journal of Basic Medical Sciences (2021) IF: 2.699
    Corilagin potential in inhibiting oxidative and inflammatory stress in LPS-induced murine macrophage cell lines (RAW 264.7)

    DOI: 10.22038/IJBMS.2021.59348.13174
    Sample: RAW 264.7 cell
  424. JOURNAL OF FOOD BIOCHEMISTRY (2022) IF: 2.72
    The immune-enhancing effect and in vitro antioxidant ability of different fractions separated from Colla corii asini

    DOI: 10.1111/jfbc.14174

    PMID: 35415887

    		 Sample: RAW 264.7 cell
  425. JOURNAL OF FOOD BIOCHEMISTRY (2021) IF: 2.72
    Impact of Thymus vulgaris extract on sodium nitrite-induced alteration of renal redox and oxidative stress: Biochemical, molecular, and immunohistochemical study

    DOI: 10.1111/jfbc.13630

    PMID: 33769578

    		 Sample: Serum,Tissue homogenate(kidney)
  426. JOURNAL OF FOOD BIOCHEMISTRY (2021) IF: 2.72
    Buchholzia coriacea seed (wonderful kolanut) alleviates insulin resistance, steatosis, inflammation and oxidative stress in high fat diet model of fatty liver disease

    DOI: 10.1111/jfbc.13836

    PMID: 34184286

    		 Sample: plasma
  427. JOURNAL OF FOOD BIOCHEMISTRY (2022) IF: 2.72
    Broccoli microgreens have hypoglycemic effect by improving blood lipid and inflammatory factors while modulating gut microbiota in mice with type 2 diabetes

    DOI: 10.1111/jfbc.14145

    PMID: 35348219

    		 Sample: serum
  428. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2022) IF: 2.723
    The Berberis vulgaris L. extract berberine exerts its anti-oxidant effects to ameliorate cholesterol overloading–induced cell apoptosis in the primary mice hepatocytes: an in vitro study

    DOI: 10.1007/s11626-022-00737-z
    Sample: serum
  429. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2022) IF: 2.723
    Hace1 overexpression mitigates myocardial hypoxia/reoxygenation injury via the effects on Keap1/Nrf2 pathway

    DOI: 10.1007/s11626-022-00725-3

    PMID: 36251153

    		 Sample: Primary cardiac cells
  430. Journal of Physiological Sciences (2022) IF: 2.781
    MiR-18a-3p improves cartilage matrix remodeling and inhibits inflammation in osteoarthritis by suppressing PDP1

    DOI: 10.1186/s12576-022-00827-3

    PMID: 35148687

    		 Sample: ATDC5 cell
  431. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018) IF: 2.784
    miR-124/MCP-1 signaling pathway modulates the protective effect of itraconazole on acute kidney injury in a mouse model of disseminated candidiasis

    DOI: 10.3892/ijmm.2018.3564
    Sample: serum
  432. PLoS One (2017) IF: 2.806
    Therapeutic effect of imiquimod on dextran sulfate sodium-induced ulcerative colitis in mice

    DOI: 10.1371/journal.pone.0186138
    Sample: Serum
  433. PLoS One (2017) IF: 2.806
    Chronic administration of mitochondrion-targeted peptide SS-31 prevents atherosclerotic development in ApoE knockout mice fed Western diet

    DOI: 10.1371/journal.pone.0185688
    Sample: Serum
  434. BMC Complementary and Alternative Medicine (2020) IF: 2.833
    4-Hydroxyisoleucine relieves inflammation through iRhom2-dependent pathway in co-cultured macrophages and adipocytes with LPS stimulation

    DOI: 10.1186/s12906-020-03166-1

    PMID: 33298044

    		 Sample: Cell sample
  435. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy (2020) IF: 2.842
    Isomangiferin Attenuates Renal Injury in Diabetic Mice via Inhibiting Inflammation

    DOI: 10.2147/DMSO.S276229

    PMID: 33204133

    		 Sample: Serum,Tissue homogenate
  436. MOLECULES (2017) IF: 2.861
    Capparis spinosa Fruit Ethanol Extracts Exert Different Effects on the Maturation of Dendritic Cells

    DOI: 10.3390/molecules22010097
    Sample: Cell culture supernatant
  437. NEUROBIOLOGY OF LEARNING AND MEMORY (2021) IF: 2.877
    GLP-1R activation ameliorated novel-object recognition memory dysfunction via regulating hippocampal AMPK/NF-κB pathway in neuropathic pain mice

    DOI: 10.1016/j.nlm.2021.107463

    PMID: 34015440

    		 Sample: Tissue homogenate(hippocampus)
  438. FITOTERAPIA (2021) IF: 2.882
    Structure elucidation and anti-inflammatory mechanism of difengpienol C, a new neolignan isolated from Illicium difengpi

    DOI: 10.1016/j.fitote.2021.104949

    PMID: 34087408

    		 Sample: RAW264.7 cells
  439. INFLAMMATION (2018) IF: 2.884
    MiR-590-3p Attenuates Acute Kidney Injury by Inhibiting Tumor Necrosis Factor Receptor-Associated Factor 6 in Septic Mice

    DOI: 10.1007/s10753-018-0921-5

    PMID: 30392071

    		 Sample: Serum
  440. INFLAMMATION (2018) IF: 2.884
    Attenuation of Inflammation and Oxidative Stress in High-Fat-Diet-Induced Obese Mice

    DOI: 10.1007/s10753-018-0948-7
    Sample: Tissue homogenate
  441. BIOSCIENCE REPORTS (2018) IF: 2.899
    Maggot protein ameliorates dextran sulphate sodium-induced ulcerative colitis in mice

    DOI: 10.1042/BSR20181799

    PMID: 30393231

    		 Sample: Serum
  442. HUMAN & EXPERIMENTAL TOXICOLOGY (2022) IF: 2.903
    Neurotoxic 18-kDa apolipoprotein E fragment production contributes to anesthetic sevoflurane-induced tau phosphorylation and neuroinflammation in vitro:

    DOI: 10.1177/09603271221102519
    Sample: neurons
  443. MICROBIAL PATHOGENESIS (2020) IF: 2.914
    Curcumin ameliorates Staphylococcus aureus-induced mastitis injury through attenuating TLR2-mediated NF−κB activation

    DOI: 10.1016/j.micpath.2020.104054
    Sample: Serum
  444. RSC Advances (2018) IF: 2.936
    Protective effects of SKLB023 on a mouse model of unilateral ureteral obstruction by the modulation of gut microbiota

    DOI: 10.1039/C8RA08049F
    Sample: plasma
  445. INFLAMMATION (2019) IF: 2.939
    Sinomenine Attenuates Cartilage Degeneration by Regulating miR-223-3p/NLRP3 Inflammasome Signaling

    DOI: 10.1007/s10753-019-00986-3

    PMID: 30847744

    		 Sample: Serum,Cell culture supernatant
  446. BIOSCIENCE REPORTS (2020) IF: 2.942
    Atractylon treatment prevents sleep-disordered breathing-induced cognitive dysfunction by suppression of chronic intermittent hypoxia-induced M1 microglial activation

    DOI: 10.1042/BSR20192800

    PMID: 32490526

    		 Sample: Cell culture supernatant
  447. Molecular Medicine Reports (2021) IF: 2.952
    α‑rhamnrtin‑3‑α‑rhamnoside exerts anti‑inflammatory effects on lipopolysaccharide‑stimulated RAW264.7 cells by abrogating NF‑κB and activating the Nrf2 signaling pathway

    DOI: 10.3892/mmr.2021.12439

    PMID: 34523697

    		 Sample: RAW264.7 cell
  448. Molecular Medicine Reports (2019) IF: 2.952
    BCG stimulation promotes dendritic cell proliferation and expression of VDR and CYP27B1 in vitamin D‑deficient mice

    DOI: 10.3892/mmr.2019.10780
    Sample: BMDCs
  449. Molecular Medicine Reports (2020) IF: 2.952
    Astaxanthin suppresses lipopolysaccharide‑induced myocardial injury by regulating MAPK and PI3K/AKT/mTOR/GSK3β signaling

    DOI: 10.3892/mmr.2020.11443

    PMID: 32945516

    		 Sample: Serum
  450. INTERNATIONAL IMMUNOPHARMACOLOGY (2017) IF: 2.956
    Wogonin attenuates inflammation by activating PPAR-γ in alcoholic liver disease

    DOI: 10.1016/j.intimp.2017.06.013
    Sample: Serum,Cell culture supernatant
  451. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2019) IF: 2.965
    Gastrodin attenuates neuroinflammation in DOI‐induce Tourette syndrome in rats

    DOI: 10.1002/jbt.22302
    Sample: Serum,Tissue homogenate
  452. PeerJ (2021) IF: 2.984
    Glucosylceramide synthase regulates hepatocyte repair after concanavalin A-induced immune-mediated liver injury

    DOI: 10.7717/peerj.12138

    PMID: 34611503

    		 Sample: serum
  453. PeerJ (2022) IF: 2.984
    3,4-dihydroxyphenylethyl alcohol glycoside reduces acetaminophen-induced acute liver failure in mice by inhibiting hepatocyte ferroptosis and pyroptosis

    DOI: 10.7717/peerj.13082

    PMID: 35310165

    		 Sample: plasma
  454. TRANSPLANTATION PROCEEDINGS (2022) IF: 1.066
    A Novel Hepatectomy Model in Mice Using a Gutta Cutter Tool: A Feasibility Study and Preliminary Results

    DOI: 10.1016/j.transproceed.2022.01.029

    PMID: 35287968

    		 Sample: serum
  455. GENERAL PHYSIOLOGY AND BIOPHYSICS (2020) IF: 1.07
    The TrkB agonist 7,8-dihydroxyflavone improves sensory-motor performance and reduces lipid peroxidation in old mice.

    DOI: 10.4149/gpb_2020022
    Sample: cortex
  456. BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT (2020) IF: 1.186
    Human umbilical cord mesenchymal stem cells suppress lung cancer via TLR4/NF-κB signalling pathway

    DOI: 10.1080/13102818.2020.1712257
    Sample: Lewis cell-xenograft
  457. Current Medical Science (2020) IF: 1.273
    Role of Interleukin 17A in Aortic Valve Inflammation in Apolipoprotein E-deficient Mice

    DOI: 10.1007/s11596-020-2230-0

    PMID: 32862384

    		 Sample: Plasma
  458. International Journal of Clinical and Experimental Medicine (2015) IF: 1.277
    Sulfated modification promotes the immunomodulatory bioactivities of Lyciumbarbarum polysaccharides in vitro

    PMID: 26884954

    		 Sample: lymphocyte
  459. Medical Molecular Morphology (2019) IF: 1.383
    The therapeutic effects of resveratrol on hepatic steatosis in high-fat diet-induced obese mice by improving oxidative stress, inflammation and lipid-related gene transcriptional expression

    DOI: 10.1007/s00795-019-00216-7

    PMID: 30673851

    		 Sample: Serum,Tissue homogenate
  460. International Journal of Clinical and Experimental Pathology (2018) IF: 1.396
    An experimental hyperlipidemia model with periodontitis in mice

    PMID: 31938106

    		 Sample: serum
  461. Experimental and Therapeutic Medicine (2018) IF: 1.41
    miR‑148a inhibits pro‑inflammatory cytokines released by intervertebral disc cells by regulating the p38/MAPK pathway

    DOI: 10.3892/etm.2018.6516
    Sample: Cell culture supernatant
  462. JOURNAL OF APPLIED ANIMAL WELFARE SCIENCE (2021) IF: 1.44
    Enriched environment during adolescence modulates lipid metabolism and emotion-related behaviors in mice

    DOI: 10.1080/10888705.2021.1972421

    PMID: 34470518

    		 Sample: serum
  463. BIOLOGICAL & PHARMACEUTICAL BULLETIN (2019) IF: 1.54
    Chemerin-9 Peptide Enhances Memory and Ameliorates Aβ1-42-induced Object Memory Impairment in Mice

    DOI: 10.1248/bpb.b19-00510
    Sample: hippocampus
  464. Oncology Letters (2018) IF: 1.664
    The association between inflammation, the microbiome and urethane-induced pulmonary adenocarcinoma Corrigendum in /10.3892/ol.2018.9063

    DOI: 10.3892/ol.2018.8167
    Sample: Serum
  465. Molecular Medicine Reports (2017) IF: 1.692
    Bone marrow mesenchymal stem cells accelerate the hyperglycemic refractory wound healing by inhibiting an excessive inflammatory response

    DOI: 10.3892/mmr.2017.6400
    Sample: Skin tissue
  466. Food Science & Nutrition (2020) IF: 1.797
    Subcutaneous administration of casein attenuates atherosclerotic progression in male apoE-/- mice fed with high-fat diet

    DOI: 10.1002/fsn3.1638
    Sample: Plasma
  467. Evidence-based Complementary and Alternative Medicine (2020) IF: 1.813
    Antioxidant and Anti-Inflammatory Activities of Kigelia africana (Lam.) Benth.

    DOI: 10.1155/2020/4352084
    Sample: RAW 264.7 cell
  468. Molecular Medicine Reports (2019) IF: 1.851
    Synergistic protection of matrine and lycopene against lipopolysaccharide‑induced acute lung injury in mice

    DOI: 10.3892/mmr.2019.10278
    Sample: lung
  469. Molecular Medicine Reports (2019) IF: 1.851
    Kisspeptin‑13 inhibits bleomycin‑induced pulmonary fibrosis through GPR54 in mice

    DOI: 10.3892/mmr.2019.10341
    Sample: lung
  470. International Heart Journal (2022) IF: 1.862
    Adipose-Derived Stem Cells-Derived Exosomes with High Amounts of Circ_0001747 Alleviate Hypoxia/Reoxygenation-Induced Injury in Myocardial Cells by Targeting MiR-199b-3p/MCL1 Axis

    DOI: 10.1536/ihj.21-441

    PMID: 35354755

    		 Sample: HL-1 cell
  471. BIOMEDICAL AND ENVIRONMENTAL SCIENCES (2019) IF: 1.917
    Effects of Simulated Heat Wave and Ozone on High Fat Diet ApoE Deficient Mice

    DOI: 10.3967/bes2018.101
    Sample: Plasma,Tissue homogenate
  472. MEDICAL SCIENCE MONITOR (2020) IF: 1.918
    The Effects of RKI-1447 in a Mouse Model of Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet and in HepG2 Human Hepatocellular Carcinoma Cells Treated with Oleic Acid

    DOI: 10.12659/MSM.919220

    PMID: 32026851

    		 Sample: Serum,Cell culture supernatant,Tissue homogenate
  473. Molecular Medicine Reports (2018) IF: 1.922
    Oral supplementation with ursolic acid ameliorates sepsis-induced acute kidney injury in a mouse model by inhibiting oxidative stress and inflammatory responses

    DOI: 10.3892/mmr.2018.8767
    Sample: Serum
  474. Molecular Medicine Reports (2018) IF: 1.922
    Embelin inhibits abdominal aortic aneurysm through decreasing IL‑6‑induced STAT3 and NF‑κB inactivation

    DOI: 10.3892/mmr.2018.9221
    Sample: Aortic tissues
  475. Molecular Medicine Reports (2018) IF: 1.922
    Dioscin prevents LPS‑induced acute lung injury through inhibiting the TLR4/MyD88 signaling pathway via upregulation of HSP70

    DOI: 10.3892/mmr.2018.8667
    Sample: Serum,Tissue homogenate
  476. Journal of Biomedical Research (2021)
    Protective effects on acute hypoxic-ischemic brain damage in mfat-1 transgenic mice by alleviating neuroinflammation

    DOI: 10.7555/JBR.35.20210107
    Sample: brain tissue
  477. Biomedical Reports (2020)
    Neuroprotective effect of Mulmina™ against chemotherapy‑induced cognitive decline in normal mice Erratum in /10.3892/br.2021.1433

    DOI: 10.3892/br.2020.1377
    Sample: brain
  478. Veterinary World (2019)
    Golden sea cucumber extract revives glucose transporter-4 and interleukin-6 protein level in diabetic mouse muscle

    DOI: 10.14202/vetworld.2019.684-688

    PMID: 31327904

    		 Sample: Tissue homogenate
  479. PharmaNutrition (2022)
    Crocin Suppresses Inflammation-Induced Apoptosis in rmTBI Mouse Model Via Modulation of Nrf2 Transcriptional Activity

    DOI: 10.1016/j.phanu.2022.100308
    Sample: brain cortex
  480. Advances in Pharmacological and Pharmaceutical Sciences (2020)
    Antihypernociceptive, Anxiolytic, and Antidepressant Properties of Aqueous and Ethanol Extracts of Dissotis thollonii Cogn. (Melastomataceae) in Mice

    DOI: 10.1155/2020/8886894

    PMID: 33015629

    		 Sample: Serum,Tissue homogenate
  481. TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH (2021) IF: 0.533
    Effect of ganoderic acid on diethylnitrosamine-induced liver cancer in mice

    DOI: 10.4314/tjpr.v19i12.23
    Sample: serum
  482. FOOD SCIENCE AND BIOTECHNOLOGY (2019) IF: 0.888
    Antioxidant and anti-inflammatory effects of an ethanol fraction from the Schisandra chinensis baillon hot water extract fermented using Lactobacilius paracasei subsp. tolerans

    DOI: 10.1007/s10068-019-00626-4
    Sample: RAW 264.7 cells
  483. Journal of Oleo Science (2015) IF: 0.968
    A Comparative Study of the Effects upon LPS Induced Macrophage RAW264.7 Inflammation in vitro of the Lipids of Hippocampus trimaculatus Leach

    DOI: 10.5650/jos.ess15190
    Sample: Cell culture supernatant
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Q

R*********sSubmitted [ Jul 05 2021 ]

Asked: Hello, Is E-EL-M0044 kit suitable for tissue homogenates?

Reply

A

adminSubmitted [ Jul 05 2021 ]

Answered: The E-EL-M0044 kit is suitable for mouse tissue homogenates samples.

A

adminSubmitted [ Jul 05 2021 ]

Answered: 

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