MSLN Polyclonal Antibody

Uniprot : Q13421
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14227

      Synonyms:CAK 1,CAK1,CAK1 antigen,cleaved form,Megakaryocyte potentiating factor,Mesothelin,Mesothelin isoform 1 precursor,MPF,Msln,MSLN,Pre pro megakaryocyte potentiating factor,Pre-pro-megakaryocyte-potentiating factor,SMR,SMRP,Soluble MPF mesothelin related protein

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CAK 1,CAK1,CAK1 antigen,cleaved form,Megakaryocyte potentiating factor,Mesothelin,Mesothelin isoform 1 precursor,MPF,Msln,MSLN,Pre pro megakaryocyte potentiating factor,Pre-pro-megakaryocyte-potentiating factor,SMR,SMRP,Soluble MPF mesothelin related protein
      Swissprot Q13421
      Source Rabbit
      Reactivity Human
      Immunogen Recombinant protein of human MSLN
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted and Cell membrane. Golgi apparatus.
      Tissue specificity Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.

      Images

      Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MSLN Polyclonal Antibody at dilution 1:40

      Immunohistochemistry of paraffin-embedded Human lung cancer tissue using MSLN Polyclonal Antibody at dilution 1:40

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