MT-ND1 Polyclonal Antibody
- +1
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse;Rat
- Applications: WB;IHC
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Product Details
Verified Samples |
Verified Samples in WB:Hela Verified Samples in IHC:Human thyroid cancer,Human brain |
Dilution |
WB 1:200-1:1000, IHC 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human MT-ND1 |
Abbre | MT-ND1 |
Synonyms | Complex I;subunit ND1;Mitochondrially encoded NADH dehydrogenase 1;MT-ND1;MTND1;NAD1;NADH dehydrogenase subunit 1 (complex I);NADH dehydrogenase subunit 1;NADH-ubiquinone oxidoreductase chain 1;NADH-ubiquinone oxidoreductase;subunit ND1;NADH1;ND1;NU1M |
Swissprot | |
Calculated MW | 36kDa |
Cellular Localization | Mitochondrion inner membrane. |
Concentration | 1 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Metabolism; Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Ice bag |
background | NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol