MYBPC3 Polyclonal Antibody (E-AB-63687)
For research use only.
| Verified Samples |
Verified Samples in IHC: Rat heart, Mouse heart |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human MYBPC3 (NP_000247.2). |
| Abbre | MYBPC3 |
| Synonyms | CMD1MM, CMH4, FHC, LVNC10, MYBP-C, MYBPC3, cardiac |
| Swissprot | |
| Cellular Localization | Cytoskeleton, striated muscle myosin thick filament, Cytosol, Other locations: A band, C zone, cardiac myofibril, M band, sarcomere, Z disc. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cardiovascular |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. |
Other Clones
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Other Formats
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Unconjugated
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