MYSM1 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human
- Applications: IHC
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Product Details
Verified Samples |
Verified Samples in IHC:Human ovarian cancer |
Dilution |
IHC 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human MYSM1 |
Abbre | MYSM1 |
Synonyms | 2A-DUB;2ADUB;Histone H2A deubiquitinase;Histone H2A deubiquitinase MYSM1;KIAA1915;Myb like SWIRM and MPN domains 1;Myb like;SWIRM and MPN domain containing protein;Myb like;SWIRM and MPN domains 1;Myb-like;Myb-like;SWIRM and MPN domains 1;MYSM 1;mysm1;MYSM1 Myb-like;SWIRM and MPN domains 1;MYSM1;RP4-592A1.1;SWIRM and MPN domain-containing protein 1 |
Swissprot | |
Cellular Localization | Nucleus. |
Concentration | 0.5 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol