For research use only.
| Verified Samples |
Verified Samples in IHC: Human gastric cancer, Human lymphoma |
| Dilution | IHC 1:25-1:100 |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human NES |
| Synonyms | ESTM 46, FLJ 21841, FLJ21841, Intermediate filament protein, NEST, Nbla00170, Nestin, nes |
| Swissprot | |
| Cellular Localization | Cytoskeleton, intermediate filament, intermediate filament cytoskeleton, Extracellular region or secreted, extracellular matrix, Other locations: cytoplasm. |
| Concentration | 0.2 mg/mL |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Developmental Biology, Neuroscience, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Nestin is a type IV intermediate filament protein expressed by neuroepithelial stem cells and which has been proposed to represent a marker for putative islet stem cells. It is a high molecular weight protein with a terminus greater than 500 residues. Nestins are expressed by several types of cells during development, mostly in dividing cells of the Central Nervous System, Peripheral Nervous System and myogenic tissues. It also represents the progenitor population of neural stem cell origin. The role of nestin in dynamic cells, particularly structural organization of the cell, appears strictly regulated by phosphorylation, especially its integration into heterogeneous intermediate filaments together with vimentin or internexin. Nestin has recently received attention as a marker for detecting newly formed endothelial cells. |
Other Clones
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Unconjugated
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