Current Position:Home>>Antibodies>>Polyclonal Antibody>> NF2 Polyclonal Antibody

NF2 Polyclonal Antibody

Uniprot: P35240

Catalog number:E-AB-40301

Synonyms:ACN,BANF,Bilateral acoustic neuroma,MERL,Merlin,Moesin ezrin radixin like protein,Moesin ezrin radizin like,Moesin-ezrin-radixin-like protein,Neurofibromatosis 2,Neurofibromatosis type 2,Neurofibromatosis2,Neurofibromin 2,Neurofibromin-2,Neurofibromin2,NF 2,Nf2,SCH,Schwannomerlin,Schwannomin

Size:

20μL
60μL
120μL
200μL

Qty:

- +

Price: $69

Reactivity: H

Applications: IHC

Lead Time: 7~10daysWelcome to order from local distributors.

Add to cart Compare Bulk request Manual

Datasheet
Reviews
Q&A

Overview

Synonyms	ACN,BANF,Bilateral acoustic neuroma,MERL,Merlin,Moesin ezrin radixin like protein,Moesin ezrin radizin like,Moesin-ezrin-radixin-like protein,Neurofibromatosis 2,Neurofibromatosis type 2,Neurofibromatosis2,Neurofibromin 2,Neurofibromin-2,Neurofibromin2,NF 2,Nf2,SCH,Schwannomerlin,Schwannomin
Swissprot	P35240
Reactivity	Human
Immunogen	Recombinant Human Merlin protein
Application	IHC
Recommended dilution	IHC 1:100-1:200
Concentration	2mg/mL

Properties

Cellular localization	Cytoplasm > perinuclear region
Purification	Affinity purification
Storage instructions	Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer	PBS with 0.05% Proclin300, 50% glycerol, pH7.4.
Background	This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.