Current Position:Home>>Antibodies>>Polyclonal Antibody>> NF2 Polyclonal Antibody
Catalog number:E-AB-40301
Synonyms:ACN,BANF,Bilateral acoustic neuroma,MERL,Merlin,Moesin ezrin radixin like protein,Moesin ezrin radizin like,Moesin-ezrin-radixin-like protein,Neurofibromatosis 2,Neurofibromatosis type 2,Neurofibromatosis2,Neurofibromin 2,Neurofibromin-2,Neurofibromin2,NF 2,Nf2,SCH,Schwannomerlin,Schwannomin
Reactivity: H
Applications: IHC
Lead Time: 7~10daysWelcome to order from local distributors.
Add to cart Compare Bulk request ManualSynonyms | ACN,BANF,Bilateral acoustic neuroma,MERL,Merlin,Moesin ezrin radixin like protein,Moesin ezrin radizin like,Moesin-ezrin-radixin-like protein,Neurofibromatosis 2,Neurofibromatosis type 2,Neurofibromatosis2,Neurofibromin 2,Neurofibromin-2,Neurofibromin2,NF 2,Nf2,SCH,Schwannomerlin,Schwannomin |
Swissprot | P35240 |
Reactivity | Human |
Immunogen | Recombinant Human Merlin protein |
Application | IHC |
Recommended dilution | IHC 1:100-1:200 |
Concentration | 2mg/mL |
Cellular localization | Cytoplasm > perinuclear region |
Purification | Affinity purification |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.4. |
Background | This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. |