English Toll-free:1-888-852-8623 or Contact Us
Keyword cannot be empty !

NTRK1 Polyclonal Antibody

Cat:E-AB-12668
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse;Rat
  • Applications: IHC
Add to cart

For research use only. Order now, ship in 3 days

Product Details
Verified Samples Verified Samples in IHC:Human colon cancer,Human ovarian cancer
Dilution

IHC 1:100-1:300

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human NTRK1
Abbre NTRK1
Synonyms gp140trk;High affinity nerve growth factor receptor;High affinity nerve growth factor receptor precursor;MTC;Neurotrophic tyrosine kinase receptor type 1;NTRK1;NTRK1;Oncogene TRK;p14-TrkA;p140 TrkA;p140-TrkA;Slow nerve growth;Trk A;TRK;Trk-A;TRK1;TRK1-transforming tyrosine kinase protein;Tropomyosin-related kinase A;Tyrosine kinase receptor A;Tyrosine kinase receptor
Swissprot
Cellular Localization Cell membrane. Early endosome membrane. Late endosome membrane. Internalized to endosomes upon binding of NGF or NTF3 and further transported to the cell body via a retrograde axonal transport. Localized at cell membrane and early endosomes before nerve growth factor (NGF) stimulation. Recruited to late endosomes after NGF stimulation. Colocalized with RAPGEF2 at late endosomes (By similarity).
Concentration 0.8 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.